A Study on Changes in Blood Eosinophil, Serum IgE and T Lympocyte Subpopulation after Sochongryongtang to Asthmatic Patients

소청룡탕치료 기관지천식환자의 혈액내 호산구수와 혈청IgE 및 T림프구아형의 변화

  • Jung, Hee-Jae (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Ju, Chang-Yeop (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Jae-Sung (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Kyung-Ki (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Rhee, Hyung-Koo (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Jung, Sung-Ki (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Hwang, Woo-Suck (Division of Repiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University)
  • 정희재 (경희대학교 한의과대학 폐계내과학교실) ;
  • 주창엽 (경희대학교 한의과대학 폐계내과학교실) ;
  • 이재성 (경희대학교 한의과대학 폐계내과학교실) ;
  • 이경기 (경희대학교 한의과대학 폐계내과학교실) ;
  • 이형구 (경희대학교 한의과대학 폐계내과학교실) ;
  • 정승기 (경희대학교 한의과대학 폐계내과학교실) ;
  • 황우석 (경희대학교 한의과대학 폐계내과학교실)
  • Published : 2002.03.30

Abstract

Background : Nowadays asthma is considered to be an inflamatory disease characterized by airborne hyper-responsiveness and pulmonary eosinophilia. Objective : We aimed to identify the effects of Sochongryongtang on blood eosinophil, serum IgE and T lympocyte subpopulation in asthmatic patients. Material and Methods : The subjects consisted of fifteen patients with asthma who had been treated with Sochongryongtang for two weeks from February 2001 through June 2001. Sochongryongtang is herbal decoction which has been used for the traditional therapeutic agent of asthma. Results : The blood eosinophil and serum IgE in a normal controlled group. However, the T lympocyte subpopulation in asthmatic patients was not significantly different from the T lympocyte subpopulation in a normal group. The patients were treated with Sochongryongtang for two weeks. No significant difference in the blood eosinophil, serum IgE and T Iympocyte in the sub population. After treatment with Sochongryongtang for two weeks, FEV 1 increased significantly over 0.5 points out of total scores. Conclusion : This study shows that Sochongryongtang has effects on improvement of pulmonary function and quality of life in asthmatic patients. However, the patients who were treated with Sochongryongtang for two weeks showed no significant difference in the blood eosinophil, serum IgE and T lympocyte subpopulation. Further long-term studies must be made on a large number of asthmatic patients.

Keywords

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