Korean Journal of Acupuncture

  • 제19권1호
  • /
  • Pages.47-56
  • /
  • 2002
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  • 2287-3368(pISSN)
  • /
  • 2287-3376(eISSN)
경락경혈학회 (Society for Meridian and Acupoint)
권호 표지

침자(鍼刺)가 혈압(血壓) 및 신경계(神經系) 혈압중추(血壓中樞) c-fos 발현에 미치는 영향(影響)

The Effect of LR3 Acupuncture on Blood Pressure and C-fos Expression in Hypertensive Rats Induced by 2K1C

  • 강동환 (동신대학교 한의과대학 경혈학교실) ;
  • 윤여충 (동신대학교 한의과대학 침구학교실) ;
  • 김정상 (동신대학교 한의과대학 해부학교실) ;
  • 김원재 (전남대학교 치과대학 생리학교실) ;
  • 나창수 (동신대학교 한의과대학 경혈학교실)
  • Kang Dong-Hwan (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Yun Yeo-Chung (Dept. of Acupucture & Moxibustion, College of Oriental Medicine, Dongshin University) ;
  • Kim Jeong-Sang (Dept. of Anatomy, College of Oriental Medicine, Dongshin University) ;
  • Kim Won-Jae (Dept. of Oral Physiology, College of dentistry, Chonnam National University) ;
  • Na Chang-Su (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University)
  • 발행 : 2002.03.27
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초록

The frequency of the hypertension is increasing as the life level is improved and an average span of the life is extended since we approached modern stage. The hypertension is also dangerous disease which raises fatal complication for example with the bleeding aproplexy and the ischemic attack. The medicinal treatment about the hypertension is required patients to take continually. The acupuncture have been introduced because a medicine-chemical treatment hasn't good influence on the human body. It recently has been processed that studies acupuncture effect for blood pressure and have been found out that blood pressure go down. The object of this study observe the effect of LR3 acupuncture on hypertension in Renal Hypertension RAT induced by 2K1C. The 2K1C model was based on renin-angiotensin system. We put the silver clip in renal artery to induce renal hypertension. We try to observe that LR3 acupuncture influence on the blood pressure and c-fos expression in CVLM, NTS, RVLM. In results, the blood pressure was decreased during acupuncture than before acupuncture, after acupuncture. The heart rate was also decreased during acupuncture than before acupuncture, after acupuncture. The LR3 acupuncture significantly effects on blood pressure and heart rate (P<0.05). The increased expression of c-fos was shown in CVLM, NTS, but not in RVLM. In conclusion, LR3 was relived the action of control upon the hypertension and related with medulla, particularly CVLM, NTS. It needs to be closely examined pharmacological mechanism and studied combination with other acupoints.

키워드

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