대한한의학방제학회지 (Herbal Formula Science)

  • 제10권2호
  • /
  • Pages.243-249
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  • 2002
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  • 1229-1218(pISSN)
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  • 2288-5641(eISSN)
대한한의학방제학회 (The Korean Medicine Society for the Herbal Formula Study)
권호 표지

솔잎 발효액(醱酵液)의 항산화효과(抗酸化效果)

Antioxidative effects of the fermented extract of Pinus densiflora

  • 문연자 (원광대학교 한의학전문대학원, 한약자원개발학과) ;
  • 임난영 (원광대학교 한의학전문대학원, 한약자원개발학과) ;
  • 이성원 (원광대학교 한의학전문대학원, 한약자원개발학과) ;
  • 강대길 (원광대학교 한의학전문대학원, 한약자원개발학과) ;
  • 백순기 (동신대학교 환경공학과) ;
  • 우원홍 (원광대학교 한의학전문대학원, 한약자원개발학과)
  • Mun Yeun-Ja (Department of herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwag University) ;
  • Lim Nan-Young (Department of herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwag University) ;
  • Lee Sung-Won (Department of herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwag University) ;
  • Kang Dae-Gill (Department of herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwag University) ;
  • Baik Soon-Ki (Dept. of Environmental Eng. Dongshin University) ;
  • Woo Won-Hong (Department of herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwag University)
  • 발행 : 2002.12.30
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초록

This study was performed to investigate the effects of fermented extract of Pinus densiflora (FPD) on oxygen radicals and $H_2O_2$-induced damage. The results are as follows: 1. The 1.1-diphenyl-2-picrylhydrazyl (DPPH) free radicals were considerably reduced by FPD and $IC_{50}$ value was showed the concentration of 20 ㎍／㎖. 2. The cytotoxicity did not observe by FPD treatment in A548 cells. 3. The $H_2O_2$-induced cell damage was recovered by FPD pretreatment in A549 cells. These results suggest that FPD, as a natural antioxidant, has scavenging effect of free radicals and protection effect from $H_2O_2$-induced cytotoxicity.

키워드

참고문헌

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