Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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THE EFFECT ON GUIDED BONE REGENERATION OF THE CHITOSAN MEMBRANE

키토산 차단막의 유도골재생 효과

  • Moon, Jin-Suk (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
  • Park, Young-Ju (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
  • Park, Jun-Woo (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
  • Lee, Yong-Chan (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
  • Cho, Byoung-Ouck (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
  • Ahn, Byoung-Keun (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University)
  • 문진석 (한림대학교 의과대학 구강악안면외과학교실) ;
  • 박영주 (한림대학교 의과대학 구강악안면외과학교실) ;
  • 박준우 (한림대학교 의과대학 구강악안면외과학교실) ;
  • 이용찬 (한림대학교 의과대학 구강악안면외과학교실) ;
  • 조병욱 (한림대학교 의과대학 구강악안면외과학교실) ;
  • 안병근 (한림대학교 의과대학 구강악안면외과학교실)
  • Published : 2002.08.31
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Abstract

Using the rat's skull, the study on the biodegradability and guided bone regeneration of the chitosan membrane was performed. The results are as follows: 1. The biodegradability of the chitosan membrane could not be confirmed, but after 12 weeks, this membrane did not yet break into small pieces and there was no specific local tissue reaction. 2. It was not certain whether the pore size of this membrane was affected on osteoblastic activity. 3. After 6 weeks, the bony defect area of rat's skull was not completely filled, but on high magnification it showed that the osteoclasts and the osteoblasts were observed in the regenerating area. In conclusion, the chitosan membrane developed in this study was fit for guided bone regeneration.

Keywords

References

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