Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Free Radical Scavengers from the Leaves of Albizzia julibrissin

자귀나무 잎의 자유라디칼 소거 물질

  • Jang, Kyu-Gwan (Botanical Garden, Wonkwang University) ;
  • Oh, Hyun-Cheol (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Ko, Eun-Kyung (MRRC and College of Pharmacy, Wonkwang University) ;
  • Kang, Ki-Hong (MRRC and College of Pharmacy, Wonkwang University) ;
  • Park, Sung-Eun (MRRC and College of Pharmacy, Wonkwang University) ;
  • Oh, Myung-Hun (MRRC and College of Pharmacy, Wonkwang University) ;
  • Kim, Youn-Chul (MRRC and College of Pharmacy, Wonkwang University)
  • Published : 2002.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

Assay-guided fractionation of the methanol extract of the leaves of Albizzia julibrissin has furnished quercitrin (1) and afzelin (2) as the scavengers of DPPH radical. Quercitrin and afzelin showed scavenging activity of DPPH free radical with the $IC_{50}$ values of 17.3 and 71.5 ${\mu}M$, respectively.

Keywords

References

  1. Halliwell, B. and Gutteridge, J. M. (1984) Lipid peroxidation, oxygen radicals, cell damage and anti-oxidant therapy.Lancet 23: 1396-1397
  2. 배기환(2000) 한국의 약용식물, 239. 교학사, 서울
  3. Ikeda, T., Fujiwara, S., Araki, K., Kinjo, J., Nohara, T. andMiyoshi, T. (1997) Cytotoxic glycosides from Albizziajulibrissin. J. Nat. Prod. 60: 102-107 https://doi.org/10.1021/np960556t
  4. Zou, K., Zhao, Y., Tu, G., Cui, J., Jia, Z. and Zhang, R.(2000) Two diastereomeric saponins with cytotoxic activityfrom Albizzia julibrissin. Carbohydr. Res. 324: 182-188 https://doi.org/10.1016/S0008-6215(99)00294-3
  5. Kang, T. H., Jeong, S. J., Kim, N. Y., Higuchi, R. and Kim,Y. C. (2000) Sedative activity of two flavonol glycosidesisolated from the flowers of Albizzia julibrissin Durazz. J.Ethnopharmacol. 71: 321-323 https://doi.org/10.1016/S0378-8741(99)00202-0
  6. Kumar, V. P., Shashidhara, S., Kumar, M. M. and Sridhara,B. Y. (2000) Effect of Luffa echinata on lipid peroxidationand free radical scavenging activity. J. Pharm. Pharmacol.52: 891-894 https://doi.org/10.1211/0022357001774589
  7. Lee, J. H., Kwon, Y. S. and Kim, C. M. (1998) Flavonoidsfrom the stem bark of Platycarya strobilacea. Kor. J.Pharmacogn. 29: 353-356
  8. Lee, M. H., Lin, R. D., Shen, L. Y, Yang, L. L., Yen, K. Y.and Hou, W. C. (2001) Monoamine oxidase B and free radical scavenging activities of natural flavonoids inMelastoma candidum D. Don. J. Aeric. Food Chem. 49:5551-5555 https://doi.org/10.1021/jf010622j
  9. Noroozi, M., Angerson, W. J. and Lean, M. E. (1998) Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes. Am. J. Clin. Nutr. 67: 1210-1218 https://doi.org/10.1093/ajcn/67.6.1210