Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Screening of the Inhibitory Activity of Medicinal Plants against VHR Dual-Specificity Protein Tyrosine Phosphatase (DS- PTPase)

생약의 VHR Dual - Specificity Protein Tyrosine Phosphatase (DS-PTPase) 저해 활성 검색

  • Lee, Myung-Sun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Bae, Eun-Young (Korea Research Institute of Bioscience and Biotechnology) ;
  • Oh, Won-Keun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Ahn, Soon-Cheol (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Bo-Yeon (Korea Research Institute of Bioscience and Biotechnology) ;
  • Sohn, Cheon-Bae (Department of Food and Nutrition, Chungnam National University) ;
  • Ahn, Jong-Seog (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2002.03.30
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Abstract

The methanol extracts of 162 herbal medicines were screened for the inhibitory activity against VHR dualspecificity protein tyrosine phosphatase (DS-PTPase). Seventeen medicinal plants, Scutellaria baicalensis, Cuscuta chinensis, Caesalpinia sappan, Arecae pericarpium, Rubus coreanus, Machilus thunbergii, Amsonia elliptica Cinnamomum cassia, Arisaema erubescens, Pueraria thunbergiana, Dendrobium moniliforme, Mentha arvensis, Peucedanum japonicum, Salvia miltiorrhiza, Leonurus sibiricus, Siegesbeckia orientalis, Prunella vulgaris showed potent VHR DS-PTPase inhibitory activity.

Keywords

References

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