Natural Product Sciences

  • 제8권4호
  • /
  • Pages.129-132
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  • 2002
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  • 1226-3907(pISSN)
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  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

Antioxidant Compounds from Twig of Morus alba

  • Jin, Wen-Yi (College of Pharmacy, Chungnam National University) ;
  • Na, Min-Kyun (College of Pharmacy, Chungnam National University) ;
  • An, Ren-Bo (College of Pharmacy, Chungnam National University) ;
  • Lee, Hyun-Yong (College of Pharmacy, Chungnam National University) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University)
  • 발행 : 2002.12.01
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초록

The MeOH extract of the twig of Morus alba L. (Moraceae) inhibited strong lipid peroxidation activity. In order to find out active principle from the plant, acivity-guided fractionation was performed and five antioxidant compounds were isolated. Their chemical structures were identified as 6-geranylapigenin (1), 6-geranylnorartocarpetin (2), resveratrol (3), oxyresveratrol (4) and quercetin (5) by physicochemical and spectrometric methods. Compounds 1-5 significantly inhibited lipid peroxidation in rat brain homogenate $(IC_{50}\;values\;of\;3.37,\;3.74,\;0.23,\;0.29\;and\;0.06\; {\mu}M,\;respectively)$.

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참고문헌

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