The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)
- Volume 16 Issue 2
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- Pages.187-197
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- 2002
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- 1226-8038(pISSN)
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- 2287-9463(eISSN)
Comparision of Decoction and Distillation drug prescribed the Apricot Seed and Other Herbs on the Proliferation and Differentiation of Preadipocyte from the C57BL/6 Mouse
행인(杏仁)을 비롯한 한약복합방(韓藥複合方)이 생쥐 전지방세포(前脂肪細胞) 3T3-L1의 증식(增殖)과 분화(分化)에 미치는 영향(影響)
- Chae, Ki-Won (Dept. of Oriental Pediatrics, College of Oriental Medicine, Kyung Hee University) ;
- Lee, Jin-Yong (Dept. of Oriental Pediatrics, College of Oriental Medicine, Kyung Hee University)
- Published : 2002.12.31
Abstract
Objective: This study was proceeded to determine to what extent the decoction recipes and distillation recipes extracted from the infusion of the apricot seed and other herbs respectively would produce an effect on the proliferation and the differentiation of Preadipocyte 3T3-L1 Model separated from C57BL/6 mouse. Method: Preadipocyte 3T3-L1 Model was formed from the fat tissue of the epididymis organ, which was removed from 4-week-old C57BL/6 mouse and then was treated with collagenase. Results: 1. Concerning the restraint effect of proliferation on Preadipocyte 3T3-L1 Model, the decoction recipes, in the state of low consistency, were proved to be more effective than the distillation recipes. 2. Concerning the restraint effect of differentiation on Preadipocyte 3T3-L1 Model, the decoction recipes were shown to be more effective.