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Synthesis and Anticonvulsant Evaluation of 5-Vinyl-pyrrolidin-2-ones: A Potential GABA-AT Inhibitor

  • Published : 2002.06.20
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Abstract

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References

  1. Metcalf, B. W. Biochemical Pharmacology 1979, 28, 1705 and references cited therein https://doi.org/10.1016/0006-2952(79)90529-X
  2. Ommaya, A. K. Adv. Neurology 1976, 15, 332.
  3. Barbeau, A. Lancet II 1973, 1499.
  4. Roberts, E. Biochem. Pharmac. 1974, 23, 2637.
  5. Perry, T. L.; Hansen, S.; Kloster, M. N. New Engl. J. Med. 1973, 288, 337. https://doi.org/10.1056/NEJM197302152880703
  6. Palfreymen, M. G.; Heot, S.; Lippert, B.; Schechter, P. J. Eur. J. Pharmac. 1978, 50, 325. https://doi.org/10.1016/0014-2999(78)90138-3
  7. Roberts, E.; Kuriyama, K. Brain Res. 1968, 8, 1. https://doi.org/10.1016/0006-8993(68)90170-4
  8. Roberts, E. Neurosci. Res. Program Bull. 1972,10, 468.
  9. Silverman, R. B. Methods Enzymol. 1995, 249, 240. https://doi.org/10.1016/0076-6879(95)49038-8
  10. Tassinari, C. A.; Michelucci, R.; Ambrosetto, G.; Salvi, F. Arch. Neurol. 1987, 44, 907. https://doi.org/10.1001/archneur.1987.00520210009010
  11. Browne, T. R.; Mattson, R. J.; Penry, J. K.; Smith, D. B.; Treiman, D. M; Wilder, B. J.; Ben-Mensachem, E.; Miketta, R. M; Sheryy, K. M; Szabo, G. K. Br. J. Clin. Pharmaco. 1989, 27, 952.
  12. Silvermann, R. B.; Levy, M. A. Biochem. Biophys. Res. Commun. 1980, 95, 250. https://doi.org/10.1016/0006-291X(80)90731-7
  13. Silvermann, R. B.; Levy, M. A. Biochemistry 1981, 20, 1197. https://doi.org/10.1021/bi00508a022
  14. Silvermann, R. B.; Levy, M. A.; Muztar, A. J.; Hirsch, J. D. Biochem. Biophys. Res. Commun. 1981, 102, 520. https://doi.org/10.1016/0006-291X(81)91550-3
  15. Silvermann, R. B.; Muztar, A. J.; Levy, M. A.; Hirsch, J. D. Life Sci. 1983, 32, 2717. https://doi.org/10.1016/0024-3205(83)90391-0
  16. Silvermann, R. B. Mechanism-Based Enzyme Inactivation: Chemistry andEnzymology; CRC Press: Boca Raton, 1988; Vols. I and II.
  17. Silvermann, R. B.; Inverdo, B. J. Biochemistry 1986, 25, 6817. https://doi.org/10.1021/bi00370a013
  18. Zezza, C. A.; Kwon, T. W.; Sheu, I. ; Smith, M. B. Heterocy-cles 1992, 34, 1325. https://doi.org/10.3987/COM-92-6011
  19. Smith, M. B.; Shroff, H. N. J. Org. Chem. 1984, 49, 2900. https://doi.org/10.1021/jo00190a012
  20. Kwon, T. W.; Keusenkothen, P. E; Smith, M. B. J. Org. Chem. 1992,57,6169. https://doi.org/10.1021/jo00049a023
  21. Silvermann, R. B.; Levy, M. A. J. Org. Chem. 1980, 45, 815 https://doi.org/10.1021/jo01293a011
  22. Adkins, H.; Billica, H. R. J. Am. Chem. Soc. 1948, 70, 3121. https://doi.org/10.1021/ja01189a085
  23. Zezza, C. A.; Smith, M. B. Synth. Commun. 1987, 17, 729. https://doi.org/10.1080/00397918708075748
  24. Smith, M. B.; Shroff, H. N. Heterocycles 1985, 23, 2229. https://doi.org/10.3987/R-1985-09-2229
  25. Swinyard, E. A.; Woodhead, I. H.; White, H. S.; Franklin, M. R. General Principles, Experimental Section, Quantification and Evaluation of Anticonvulsants in Antiepileptic Drugs, 3rd Ed.; Levy, R., Ed.; Ravan Press: New York, 1988; p 88.
  26. Krall, R. L.; Penry, J. K.; White, B. G.; Kupferberg, H. J.; Swinyard, C. A. Epilepsia 1978,19, 409. https://doi.org/10.1111/j.1528-1157.1978.tb04507.x

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