한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제14권1호
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- Pages.129-153
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- 2001
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
升麻葛根湯加味方이 제I형 알레르기를 실험적으로 유발한 흰쥐의 免疫細胞및 血淸IgE에 미치는 영향
The Effects of sumgmagalguntanggamibang(SMG) on the Immunocyte and Serum IgE in the Murine of type I Hypersensitivity Induced by the Experiment
- 발행 : 20010500
초록
Background: SMG (升麻葛根湯加味方) is an herbal medicine which has been used in oriental medicine as a traditional therapeutic agent of pruritus and skin disease. Objective: This study was performed to investigate the effect of SMG on the anti-hypersensitivity and immune response in the murine of type I hypersensitivity induced by the experiment. Materials and Methods: Laboratory rats were primary sensitized with OA (ovalbumin); on day 1, rats of a Control group and Sample group (SMG group) were systemically immunized by subcutaneous injection of 1mg OA and 300mg of Al(OH)3 in a total volume of 2ml saline. The rats of the sample group were orally administered with an SMG water extract for 14 days after primary immunization. On day 14 after the systemic immunization, rats received local immunization by inhaling
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