저에너지 He-Ne IR 레이저가 말초신경병증 당뇨쥐의 혈액화학 성분 변화에 미치는 영향

Effects of the low power He-Ne IR laser on the changes of the chemical components in serum of the peripheral neuropathy in diabetic rats

본 실험은 당뇨로 인한 말초신경병증에 저에너지 레이저의 효과를 알아보기 위해 것으로 흰쥐에 streptozotocin으로 당뇨를 일으켜 당뇨로 인한 말초신경병증을 유발시킨 후 He-Ne IR 레이저를 3주 동안 매일 5분간 조사하여 혈액화학 성분의 변화를 조사한 바 다음과 같은 결론을 얻었다. ALT의 활성치는 당뇨군에 비해 레이저군에서 증가하였으나 유의성은 없었다. AST의 활성치는 대조군과 당뇨군에 비해 레이저군에서 유의하게 증가되었다. LDH는 대조군에 비해 당뇨군과 레이저군에서 유의하게 감소되었다. ALP는 대조군에 비해 당뇨군과 레이저군에서 유의하게 증가되었다. CHOL은 당뇨군에 비해 레이저군에서 유의하게 감소되었다. TRlG는 당뇨군에 비해 레이저군에서 유의하게 증가되었다. CPK는 대조군과 당뇨군에 비해 레이저군에서 유의하게 증가되었다.

This studies were to investigate the effects of low power Helium-Neon Infra-Red(He-Ne IR) laser on the changes of the chemical components in serum of the peripheral neuropathy in diabetic rats. The twenty one Spraque-Dawley adult male rats were assigned to the 3 groups: the control group(N=7), the diabetic group(n=7) and the laser group(n=7). The diabetic group was induced with a single intravenous injecion of 50mg/kg body weight streptozotocin dissolved to 0.01mol/L citrate buffer, pH 4.5. The experimental1asser group was irradiated low power He-Ne IR laser for 5 minutes every day during 21 days to the diabetic group. The results were as follows: 1. ALT was increased the laser treatment group than the diabetic group. but that was not significant. 2. AST was significantly increased the laser treatment group than the control group and the diabetic group. 3. LDH was significantly decreased the diabetic group and laser treatment group. 4. ALP was significantly increased the diabetic group and laser treatment group. 5. CHOL was significantly decreased the laser treatment group than the diabetic group. 6. TRIG was significantly increased the laser treatment group than the diabetic group. 7. CPK was significantly increased the laser treatment group than the control group and the diabetic group.