BMB Reports
- Volume 34 Issue 5
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- Pages.472-477
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- 2001
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- 1976-670X(eISSN)
Mutation of Cysteine-115 to Alanine in Nicotiana glutinosa Ornithine Decarboxylase Reduces Enzyme Activity
- Lee, Yong-Sun (Department of Biochemistry, College of Science, Yonsei University) ;
- Cho, Young-Dong (Department of Biochemistry, College of Science, Yonsei University)
- Received : 2001.05.09
- Accepted : 2001.06.14
- Published : 2001.09.30
Abstract
Ornithine decarboxylase (ODC, EC 4.1.1.17) is the first and key enzyme in eukaryotic polyamine biosynthesis. The cDNA encoding ornithine decarboxylase from Nicotiana glutinosa was cloned (
Keywords
- Glutathione-S-transferase (GST);
- Nicotiana glutinosa;
- Ornithine decarboxylase;
- Site-directed mutagenesis