Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Two Cases of Acute Respiratory Distress Syndrome with Pulmonary Hemorrhage Induced by Injection of Silicone at Perineum

외음부의 실리콘액 주사에 의한 폐출혈 및 급성 호흡 곤란 증후군 2예

  • Kang, So-Eun (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Yong, Suk-Joong (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Lee, Won-Yeon (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Shin, Pyo-Jin (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Mi-Hae (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Park, Hark-Cheon (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Shim, Myung-Sook (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Choi, Hyun-Min (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Shin, Kye-Chul (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Lim, Mi-Ae (Division of drug toxicology, National Institute of Scientific Investigation) ;
  • Yang, Kyung-Moo (Department of Forensic Science, National Institute of Scientific Investigation)
  • 강소은 (연세대학교 원주의과대학 내과학 교실) ;
  • 용석중 (연세대학교 원주의과대학 내과학 교실) ;
  • 리원연 (연세대학교 원주의과대학 내과학 교실) ;
  • 신표진 (연세대학교 원주의과대학 내과학 교실) ;
  • 김미혜 (연세대학교 원주의과대학 내과학 교실) ;
  • 박학천 (연세대학교 원주의과대학 내과학 교실) ;
  • 심명숙 (연세대학교 원주의과대학 내과학 교실) ;
  • 최현민 (연세대학교 원주의과대학 내과학 교실) ;
  • 신계철 (연세대학교 원주의과대학 내과학 교실) ;
  • 임미애 (국립 과학 수사 연구소 약독물과) ;
  • 양경무 (국립 과학 수사 연구소 법의학과)
  • Published : 2001.08.30
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Abstract

Silicone fluid is a biomaterial widely used in modern cosmetic procedures because there are few side effects, considerable chemical stability and predictable physical properties. However, many local and systemic adverse reactions have reported. In particular some serious pulmonary complications have been reported such as pulmonary thromboembolism, acute respiratory distress syndrome with some cases leading to mortality. Most of the serious complicated cases were induced by an illegal silicone fluid injection. We experienced two cases of acute respiratory distress syndrome with pulmonary hemorrhage induced by an illegal silicone fluid injection. The patients were 41 & 51 year old women, who complained of dyspnea. The chest X-ray and HRCT scan findings showed a bilateral ground glass attenuation on the bilateral dependent portion of the upper and middle lung zone. The patients clinical symptoms and the radiologic and other laboratory findings were compatible with acute respiratory distress syndrome induced by the silicon fluid injection. Here we report two cases of acute respiratory distress syndrome with pulmonary hemorrhage induced by an illegal silicone injection with a review of the relevant literature.

저자들은 외음부에 불법적인 실리콘액 피하주사 후 미만성 폐출혈을 동반한 임상적으로 진단한 급성호흡곤란 증후군 2예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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