Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지

A Case of Lymphocytic Interstitial Pneumonia

Lymphocγtic Interstitial Pneumonia 1예

  • Suh, Yo-Ahn (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kim, Sang-It (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kim, Dae-Han (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kwak, Jin-Young (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Lee, Jae-Cheol (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Baek, Hee-Jong (Department of Thoracic surgery, Korea Cancer Center Hospital) ;
  • Chung, Jin-Haeng (Department of Pathology, Korea Cancer Center Hospital)
  • Published : 2001.10.30
Download PDF
⟨ Previous Next ⟩

Abstract

Lymphocytic interstitial pneumonia(LIP) is characterized by a massive infiltration of the interstitium of the lung by mature lymphocytes, plasma cells and reticuloendothelial cells. LIP may be associated with autoimmune diseases including Sj$\check{o}$grens syndrome, SLE, myasthenia gravis, pernicious anemia, autoimmune hemolytic anemia, and HIV or an EB virus infection. There is a possibility of LIP progressing to a pulmonary or systemic lymphoma. The therapeutic response to corticosteroids and/or immunosuppressive drugs varies. Here we report a case of LIP that was diagnosed by an open lung biopsy and clonality study. The patient was a 36 year-old man without autoimmune disease or HIV infection. He was admitted as a result of severe hypoxemia showing $PaO_2$ of 48.3mmHg. The patient was treated with corticosteroids after the diagnosis and had fully recovered without a sequalae or relapse.

Keywords