IMMUNE NETWORK
- Volume 1 Issue 1
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- Pages.32-35
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- 2001
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
The healing effect of rhGM-CSF on uninfected wounds
rhGM-CSF(Leucogenⓡ)의 비감염성 상처 치유 효과에 관한 연구
- Han, Seung Kyu (Department of Plastic Surgery, School of Medicine, Korea University) ;
- Kim, Byung Soo (Department of Internal Medicine, School of Medicine, Korea University) ;
- Kim, Aeree (Department of Pathology, School of Medicine, Korea University) ;
- Seo, Jae Hong (Department of Internal Medicine, School of Medicine, Korea University) ;
- Choi, Chul Won (Department of Internal Medicine, School of Medicine, Korea University) ;
- Shin, Sang Won (Department of Internal Medicine, School of Medicine, Korea University) ;
- Kim, Yeul Hong (Department of Internal Medicine, School of Medicine, Korea University) ;
- Kim, Woo Kyung (Department of Plastic Surgery, School of Medicine, Korea University) ;
- Kim, Jun Suk (Department of Internal Medicine, School of Medicine, Korea University)
- 한승규 (고려대학교 의과대학 성형외과학교실) ;
- 김병수 (고려대학교 의과대학 내과학교실) ;
- 김애리 (고려대학교 의과대학 내과학교병리학교실) ;
- 서재홍 (고려대학교 의과대학 내과학교실) ;
- 최철원 (고려대학교 의과대학 내과학교실) ;
- 신상원 (고려대학교 의과대학 내과학교실) ;
- 김열홍 (고려대학교 의과대학 내과학교실) ;
- 김우경 (고려대학교 의과대학 성형외과학교실) ;
- 김준석 (고려대학교 의과대학 내과학교실)
- Published : 2001.04.30
Abstract
Background: rhGM-CSF has been shown to enhance the migration and proliferation of endothelial cells and to promote keratinocyte growth. This study was tried to evaluate the effect of rhGM-CSF dressing on the uninfected wounds. Methods: Thirty Sprague-dawley white mice(250-300g) were selected in this study. The number of wound with the diameter of 5 mm, was 3 in left and 3 in right at the symmetric sites, respectively. The site of rhGM-CSF dressing was decided by a randomization. rhGM-CSF(