Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Facto Langerhans' Cell Histiocytosis Involving Skull - Case Report -

두개골을 침범한 Langerhans' Cell Histiocytosis - 증례보고 -

  • Son, Chan Young (Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Park, Sang Keun (Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Kim, Han Sung (Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Shin, Hyung Shik (Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Hwang, Yong Soon (Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Kim, Sang Jin (Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine)
  • 손찬영 (인제대학교 의과대학 상계백병원 신경외과학교실) ;
  • 박상근 (인제대학교 의과대학 상계백병원 신경외과학교실) ;
  • 김한성 (인제대학교 의과대학 상계백병원 신경외과학교실) ;
  • 신형식 (인제대학교 의과대학 상계백병원 신경외과학교실) ;
  • 황용순 (인제대학교 의과대학 상계백병원 신경외과학교실) ;
  • 김상진 (인제대학교 의과대학 상계백병원 신경외과학교실)
  • Received : 2001.06.12
  • Accepted : 2001.11.03
  • Published : 2001.12.31
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Abstract

Langerhans' cell histiocytosis is a rare disease showing proliferation of histiocytes in multiple organ system. Bone lesions are the most common radiolologic manifestation of Langerhans' cell hysticytosis. Extraskeletal sites of Langerhans' cell hystiocytosis involvement include the skin, lymph nodes, thymus, lungs, central nervous system, liver, pancrease, spleen, and bowel. The authors have experienced a case of Langerhans' cell histiocytosis which involved the skull. A 3-year-old female presented with soft tissue mass on right periorbital area. Plain skull X-ray showed punched out bone lesion. Computed tomography showed non-enhancing osteolytic lesion on right frontal skull. Histologic findings of an excised mass revealed pathologic features of Langerhans' cell histiocytosis.

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