Nonsecretory Multiple Myeloma with Multiple Spine Fracture - Case Report -

다발성 척추골절을 동반한 비분비형 다발성 골수종 1례 - 증례보고 -

  • Huh, Yong-Seok (Department of Neurosurgery, Korea Veterans Hospital) ;
  • Park, Kwan-Ho (Department of Neurosurgery, Korea Veterans Hospital) ;
  • Chi, Moon-Pyo (Department of Neurosurgery, Korea Veterans Hospital) ;
  • Kim, Jae-O (Department of Neurosurgery, Korea Veterans Hospital) ;
  • Kim, Jung-Chul (Department of Neurosurgery, Korea Veterans Hospital)
  • 허용석 (한국보훈병원 신경외과) ;
  • 박관호 (한국보훈병원 신경외과) ;
  • 지문표 (한국보훈병원 신경외과) ;
  • 김재오 (한국보훈병원 신경외과) ;
  • 김정철 (한국보훈병원 신경외과)
  • Received : 2001.05.28
  • Accepted : 2001.11.02
  • Published : 2001.12.28

Abstract

A case of nonsecretory multiple myeloma in a 66 year-old-woman is reported. At first, she complained severe neck pain and radiologic finding showed C2 pathologic fracture. She complained severe low back pain 4 month later and L1 compression fracture was found. The lumbar MRI showed a 1.4cm-sized round enhancing lesion in the body of T12. Bone marrow aspiration biopsy at L1 spine showed a few polymorphous and small nests of mononuclear cell. L1 lamina bone biopsy showed many abnormal plasma cells. Pathologic diagnosis was multiple myeloma. However, plasma electrophoresis and protein immunoelectrophoresis of serum and urine of patient were normal. So, it is a nonecretory multiple myeloma case and the incidence of nonsecretory multiple myeloma is known to about 1% of all multiple myeloma.

Keywords