Journal of Acupuncture Research
- 제18권3호
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- Pages.56-68
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- 2001
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
전침자극(電針刺戟)에 의한 흰쥐 중추신경계(中樞神經系)내 대사활성(代謝活性) 변화(變化)의 영상화(映像化) 연구(硏究)
2-DG Autoradiographic Imaging of Brain Activity Patterns by Electroacupuncture Stimulation in Awake Rats
- 손영주 (경희대학교 동서의학대학원 신경과학교실) ;
- 원란 (경희대학교 동서의학대학원 신경과학교실) ;
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정혁상
(경희대학교 동서의학대학원 신경과학교실) ;
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김용석
(경희대학교 한의과대학 침구학교실) ;
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박영배
(경희대학교 한의과대학 진단학교실) ;
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손낙원
(경희대학교 동서의학대학원 신경과학교실)
- Sohn, Young-Joo (Department of Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
- Won, Ran (Department of Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
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Jung, Hyuk-Sang
(Department of Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
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Kim, Yong-Suk
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
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Park, Young-Bae
(Department of Biofunctional Medicine and Diagnosis, College of Oriental Medicine, Kyung Hee University) ;
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Sohn, Nak-Won
(Department of Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University)
- 투고 : 2001.05.03
- 심사 : 2001.05.19
- 발행 : 2001.06.20
초록
Objective : Functional brain mapping study on acupuncture stimulation using the [14C]2-deoxyglucose([14C]2-DG) autoradiography provides quantitative data and visualized pathway in central nervous system(CNS). We aimed to investigate the neural pathway and spatial distribution of metabolic activity elicited in CNS on electroacupuncture stimulation using [14C]2-DG autoradiography. Methods : The study were divided into three groups by stimulation times. 45-mins stimulation group according to Sokoloffs method, 5-mins stimulation group according to Duncun's method, and 15-mins stimulation group. ;A venous catheter was equipped into right jugular vein. The rats (Sprague-Dawley rats, 230-260g) were kept fastened loosely on a holding platform without anesthesia. Electroacupuncture stimulation (5 ms, 2 Hz, 1~3 mA) were applied on the left Zusanli (ST36) acupoint and [14C]2-DG (