Risk Factors for Cerebrovascular Disorders in Koreans

뇌혈관질환 발생 위험요인 구명을 위한 코호트내 환자-대조군 연구

  • Park, Jong-Ku (Department of Preventive Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Ki-Soon (Department of Preventive Medicine, College of Medicine, Chosun University) ;
  • Lee, Tae-Yong (Department of Preventive Medicine and Public Health, College of Medicine, Chungnam National University) ;
  • Lee, Duk-Hee (Department of Preventive Medicine, College of Medicine, Kosin University) ;
  • Koh, Kwang-Wook (Department of Preventive Medicine, College of Medicine, Kosin University) ;
  • Lee, Kang-Sook (Department of Preventive Medicine, Catholic University Medical College) ;
  • Jee, Sun-Ha (Graduate School of Health Science and Management, Yonsei University) ;
  • Suh, Il (Department of Preventive Medicine and Public Health, Yonsei University College of Medicine) ;
  • Ryu, So-Yeon (Department of Preventive Medicine, College of Medicine, Chosun University) ;
  • Park, Kee-Ho (Department of Preventive Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Chun-Bae (Department of Preventive Medicine, Yonsei University Wonju College of Medicine)
  • 박종구 (연세대학교 원주의과대학 예방의학교실) ;
  • 김기순 (조선대학교 의과대학 예방의학교실) ;
  • 이태용 (충남대학교 의과대학 예방의학교실) ;
  • 이덕희 (고신대학교 의과대학 예방의학교실) ;
  • 고광욱 (고신대학교 의과대학 예방의학교실) ;
  • 이강숙 (가톨릭대학교 의과대학 예방의학교실) ;
  • 지선하 (연세대학교 보건대학원) ;
  • 서일 (연세대학교 의과대학 예방의학교실) ;
  • 류소연 (조선대학교 의과대학 예방의학교실) ;
  • 박기호 (연세대학교 원주의과대학 예방의학교실) ;
  • 김춘배 (연세대학교 원주의과대학 예방의학교실)
  • Published : 2001.06.01

Abstract

Objectives : To identify the risk factors of cerebrovascular disorders(CVD) in Koreans using a nested case-control study. Methods : The cohort consisted of beneficiaries who had taken health examinations of the Korea Medical Insurance Corporation (KMIC cohort: 115,600 persons) in 1990 and 1992 consecutively. Four hundred and twenty five (425) cases were selected following the validation of diagnosis among 2,026 reported CVD (160-168) inpatients during the year from 1993 to 1997. Controls were matched (1:1) with age and gender of the cases among inpatients without CVD during the same period. The source of data in this study were the files of the 1990 health examinations and the 1992 health questionnaires, as well as an additional telephone survey undertaken from March to November 1999. Results : In a bivariate analysis and multiple logistic regression analysis, risk factors for total CVD were hyperglycemia and hypertension. Unrespectively, the odds ratio of ex-smoker was significantly lower than that of those who had never smoked. The risk factors for ischemic CVD also were hyperglycemia and hypertension. However, only blood pressure was found to be a risk factor for hemorrhagic CVD. Hypercholesterolemia was not a risk factor for total CVD, ischemic CVD, and hemorrhagic CVD. Conclusion : We concluded that the most important risk factor for CVD (including subtype) in Koreans was hypertension.

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