Korean Journal of Veterinary Research (대한수의학회지)
- Volume 41 Issue 4
- /
- Pages.455-465
- /
- 2001
- /
- 2466-1384(pISSN)
- /
- 2466-1392(eISSN)
Morphological study of GFAP-immunoreactive cells of fetal and neonatal spinal cords of Korean native goat
한국재래산양 태아 및 신생아 척수에서 GFAP 면역반응세포에 관한 형태학적 연구
- Song, Chi-Won (National Toxicology Research Center) ;
-
Chung, Soo-Youn
(National Toxicology Research Center)
;
- Lee, Keun-Jwa (Chungnam Institute of Livestock and Veterinary Research) ;
-
Lee, Kang-Iee
(College of Oriental Medicine, Taejon University)
;
- Lee, Kyoung-Youl (College of Veterinary Medicine, Chungnam Natioinal University) ;
- Park, Il-Kwon (College of Veterinary Medicine, Chungnam Natioinal University) ;
- Park, Mi-Sun (College of Veterinary Medicine, Chungnam Natioinal University) ;
- Chung, Seung-Hyuk (College of Veterinary Medicine, Chungnam Natioinal University) ;
-
Cho, Gyu-Woan
(College of Veterinary Medicine, Chungnam Natioinal University)
;
- Kim, Moo-Kang (College of Veterinary Medicine, Chungnam Natioinal University)
- 송치원 (국립독성연구소) ;
-
정수연
(국립독성연구소)
;
- 이근좌 (충남축산위생연구소) ;
-
이강이
(대전대학교 한의과대학)
;
- 이경열 (충남대학교 수의과대학) ;
- 박일권 (충남대학교 수의과대학) ;
- 박미선 (충남대학교 수의과대학) ;
- 정승혁 (충남대학교 수의과대학) ;
-
조규완
(충남대학교 수의과대학)
;
- 김무강 (충남대학교 수의과대학)
- Accepted : 2001.09.17
- Published : 2001.12.24
Abstract
Glial fibrillary acidic protein(GFAP) is one of the intermediate filaments, and used as an astrocyte detection marker. GFAP distribution has been studied on the fetal, neonatal and aged brains. In this study, the GFAP immunoreactive cell localization and distribution in the fetal (30, 45, 60, 90, 105 and 120 days of gestation) and neonate spinal cords of Korean native goat were investigated by immunohistochemistry. Nonpolar radial glial cells initiated to appear at 45 days of gestation. GFAP-immunoreactive processes were extended from central canal to pia matter. Bipolar immumoreactive cells were transformed to monopolar and multipolar immunoreactive cells at 45 days of gestation. Multipolar astrocytes of 60 days of gestation were found within white and gray matters of spinal cord. The number of GFAP-immunoreactive cells were gradually decreased from 90 days of gestation until newborn neonate. The intensity of GFAP immunoreactivity was gradually decreased from 95 days of gestation until newborn neonate. These results suggest that the radial glial cells within the gray and white matters of spinal cord are very fast developed.