Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Immunohistochemical study on some calcium binding proteins and neurotransmitters in suprachiasmatic nucleus of the Korean native goat

한국재래산양 시각교차위핵 내 몇 가지 칼슘결합단백질과 신경전달물질의 분포에 관한 면역조직화학적 연구

  • Song, Seung-hoon (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, Heunshik S. (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, In-Se (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
  • 송승훈 (서울대학교 수의과대학 및 농생명공학부) ;
  • 이흥식 (서울대학교 수의과대학 및 농생명공학부) ;
  • 이인세 (서울대학교 수의과대학 및 농생명공학부)
  • Accepted : 2000.05.20
  • Published : 2001.06.25
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Abstract

This study was carry out to identify the distribution of calcium binding proteins; calbindin(CB), calretinin(CR) and parvalbumin(PA) in the suprachiasmatic nucleus(SCN) of the Korean native goat by immunohistochemical methods. The expression of substance P(SP), calcitonin gene-related peptide(CG-RP), neuropeptide Y(NPY), vasoactive intestinal polypeptide(VIP) and galanin(GAL) were also investigated. CR-immunoreactivity was found in both of the cell bodies and fibers in the SCN, which the CB-immunoreactivity was observed only in the fibers. The immunoreactivity for VIP was observed in both the cell bodies and fibers, but SP-, NPY, GAL-immunoreactivities were only found in the fibers. CGRP-immunoreactivity was not seen in cell body and fibers. These results suggest that VIP, SP, NPY and GAL play a neuromodulatory or/ and neurotransmitter roles in cooperation with CB and CR in SCN of the Korean native goat.

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