Synthesis and SAR of Aziridinylquinoline-5,8-diones as Agents against Malignant Tumor Cells

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J. Med. Chem. v.30 Boger, D. L.;Yasuda, M.;Mitscher, L. A.;Drake, S. D.;Kitos, P. A.;Thomson, S. C.
J. Med. Chem. v.29 Shaikh, I. A.;Johnson, F.;Grolloman, A. P.
Arch.Pharm. Res. v.17 Ryu, C. K;Kim, H. J.
J. Antibiot v.40 Take, Y.;Oogose, K.;Kubo, T.;Inouye, Y.;Nakamura, S.
Cancer Res. v.38 Bachur, N. R.;Gordon, S. L.;Gee, M. V.
J. Med. Chem. v.26 Renault, J.;Giorgi-Renault, s.;Baron, M.;Mailliet, P.;Paoletti, C.;Cros, S.;Voisin, E.
Eur, J. Med. Chem. v.23 Horowdka, B.;Mazerska, Z.;Ledochowski, A.;Cristalli, G.;Franchetti, P.;Martelli, S.
J. Med. Chem. v.32 Lin, T.-S.;Xu, S.-P;Zhu, L.-Y.;Cosby, L. A.;Sartorelli, A. C.
Tetrahedron Lett. v.41 Yoon, E. Y.;Choi, H. Y.;Shin, K. J.;Yoo, K. H.;Chi, D. Y.;Kim, D. J.
J. Org. Chem. v.27 Pratt, Y. T.
J. Heterocycl. Chem. v.13 Liao, T. K;Nyberg, W. H.;Cheng, C. C.
J. Natl. Cancer Inst. v.82 Skehan, P.;storeng, R.;Scudiero, D.;Monks, A.;McMahan, J.;Vistica, D.;Warren, T. W.;Bokesch, H.;Kenney, S.;Boyd, M. R.

ChemInform Abstract: Synthesis and SAR of Aziridinylquinoline-5,8-diones as Agents Against Malignant Tumor Cells. vol.33, pp.17, 2001, https://doi.org/10.1002/chin.200217132
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