한국자기공명학회논문지 (Journal of the Korean Magnetic Resonance Society)

한국자기공명학회 (Korean Magnetic Resonance Society)
권호 표지

$^{19}F$ MR Imaging of 5-FU Metabolism in Mice

  • Chaejoon Cheong (Magnetic Resonance Team, Korea Basic Science Institute) ;
  • Lee, Seung-C. (Magnetic Resonance Team, Korea Basic Science Institute) ;
  • Jae-G. Seo (Magnetic Resonance Team, Korea Basic Science Institute) ;
  • Kim, Sung W. (Biomolecule Research Team, Korea Basic Science Institute) ;
  • Lee, Chulhyun (Magnetic Resonance Team, Korea Basic Science Institute) ;
  • Kim, Chul S. (Magnetic Resonance Team, Korea Basic Science Institute) ;
  • Taegyun Yang (Magnetic Resonance Team, Korea Basic Science Institute)
  • 발행 : 2001.12.01
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초록

$^{19}$ F imaging of mice was carried out. For $^{19}$ F imaging, 5-flouro-uracil (5-FU) was injected into a mouse and in vivo detection of the catabolism of 5-FU to a-fluoro-P-alanine (FBAL) was carried out. The chemical shift selective (CHESS) imaging technique was employed. The 19F spectra and images give temporal and spatial information of the metabolism for 5-FU in mice.

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