한국환경성돌연변이발암원학회지 (Environmental Mutagens and Carcinogens)

한국환경성돌연변이발암원학회 (Korean Environmental Mutagen Society)
권호 표지

Mutagenicities of Workplace Chemicals in Korea

  • Maeng, Seung-Hee (Center for Occupational Toxicology, Occupational Safety and Health Research Institute) ;
  • Lee, Jong-Yun (Center for Occupational Toxicology, Occupational Safety and Health Research Institute) ;
  • Lee, Yong-Mook (Center for Occupational Toxicology, Occupational Safety and Health Research Institute) ;
  • Chung, Hai-Won (School of Public Health, Seoul National University) ;
  • Yu, Il-Je (Center for Occupational Toxicology, Occupational Safety and Health Research Institute)
  • 발행 : 2001.03.01
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초록

Bacterial reverse mutation assays were performed for 20 workplace chemicals in Korea, which were selected among workplace chemicals under the Korea Industrial Safety and Health Act (KISHA) with the occupational exposure levels (OELs). The assays were carried out by using the pre-incubation method ($37 ^{\circ}C$, 20 min) with and without metabolic activation using Salmonella typhimurium TA98, TA100, TA1535, TA1537 and E. coli WP2uvrA. The chemicals were tested at 5 concentrations both in the preliminary and the second assays. Despite the cell toxicities, there were no chemical-induced mutagenicities with or without metabolic activation in any of 20 chemicals.

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