Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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In Vitro Anti-Helicobacter pylori Activity of Panaxytriol Isolated from Ginseng

  • Bae, Eun-Ah (Department of Food and Nutrition, Kyung Hee University) ;
  • Han, Myung-Joo (Department of Food and Nutrition, Kyung Hee University) ;
  • Baek, Nam-In (Division of Life Science, Kyung-Hee University) ;
  • Kim, Dong-Hyun (College of Pharmacy and East-West Pharmacy Research Institute, Kyung-Hee University)
  • Published : 2001.08.01
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Abstract

This study investigated the effect that some polyacetylenes and protopanaxatriol, which were isolated from heated ginseng (family Araliaceae), have on inhibiting Helicobacter pylori (HP) growth. Among the compounds tested, panaxytriol was quite effective in inhibiting HP growth with an MIC of 50 ${\mu}g/ml$. Cinsenoside Rhl and protopanaxatriol weakly inhibited $H^{+}/K^{+}$-ATPase from a rat stomach.

Keywords

References

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