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The Pharmaceutical Society of Korea (대한약학회)
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Synthesis of New Salicylamide Derivatives with Evaluation of Their Antiinflammatory, Analgesic and Antipyretic Activities

  • Fahmy, H.H. (Therapeutical Chemistry Department, National Research Centre) ;
  • Soliman, G.A. (Facully Vet Med., Dept. of Pharmacology, Cairo University)
  • Published : 2001.06.01
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Abstract

A new series of pyridazine, pyrazoles, pyrazolidine-3,5-dione, Semicarbazide, thiosemicarbazides, hydantoin, thiohydantoins, 1,2,4-triazoles, S-triazolo[3,4-b]-1,3,4-thiadiazoles incorporated indirectly into salicylamide moiety at position 2 were synthesized. Also the synthesis of novel series of 3-salicylamido-2-hydroxypropyl-amino derivatives were prepared. Several of these compounds were screened for antiinflammatory, analgesic, antipyretic and ulcerogenic activities.

Keywords

References

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