한국수정란이식학회지 (Journal of Embryo Transfer)
- 제16권3호
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- Pages.239-243
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- 2001
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- 2508-755X(pISSN)
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- 2288-0178(eISSN)
마우스 성숙난자의 유리화 동결 중 Cytoskeleton Stabilizer, Taxol의 처리 후 배발달률과 산자의 생산
Post-thawed Preimplantation Development and Production of Offsprings after Vitrification using Taxol $^{TM}$ a Cytoskeleton Stabilizer
초록
Selection of oocyte cryopreservation method is a prerequisite factor for developing an effective bank system. Compared with slow freezing method, the vitrification has various advantages such as avoiding intracellular ice crustal formation. In our previous, we attempted to employ a vitrification method using ethylene glycol and an electron microscope grid for cryopreservation of mouse oocytes. However, A high incidence of spindle and chromosome abnormalities was detected in thawed oocytes after vitrification. We examined whether the addition of a cystoskeleton stabilizer Taxol