Biomolecules & Therapeutics
- Volume 9 Issue 3
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- Pages.201-208
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- 2001
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- 1976-9148(pISSN)
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- 2005-4483(eISSN)
Influence of Bromocriptine on Release of Norepinephrine and Epinephrine Evoked by Cholinergic Stimulation from the Rat Adrenal Medulla
- Lee, Seung-Il (Department of Internal Medicine, College of Medicine, Chosun University) ;
- Kang, Moo-Jin (Department of Pharmacology, College of Medicine, Chosun University) ;
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Lim, Dong-Yoon
(Department of Pharmacology, College of Medicine, Chosun University)
- Published : 2001.09.01
Abstract
The present study was conducted to examine the effects of cholinergic stimulation and membrane depolarization on secretion of epinephrine (EP) and norepinephrine (NE) in the perfused model of the rat adrenal gland and to investigate the effect of bromocriptine on secretion of EP and NE evoked by these secreta-gogues. Acetylcholine (ACh, 5.32 mM), high