Some Pharmacological Activities of Acanthoic Acid Isolated from Acanthopanax koreanum Root Bark

섬모갈피나무의 근피성분, Acanthoic acid의 약리작용

  • 이영순 (서울대학교 천연물과학연구소) ;
  • 이은방 (서울대학교 천연물과학연구소) ;
  • 김영호 (충남대학교 약학대학)
  • Published : 2001.09.01

Abstract

Some pharmacological activities of acanthoic acid, isolated from Acanthopanax koreanum root was investigated in animals. It is revealed that the compound had analgesic and anti-inflammatory activities without actions on central nervous system and showed inhibition of lipid peroxidation. The anti-inflammatory activity might be related to inhibition of prostaglandin E$_2$ synthesis in exudates of inflammation.

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