The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Immunoregulative Action of Ethyl Alcohol Fraction of Cervus nippon

녹용 에탄올 분획의 면역조절작용

  • Suh, Jeong-Sook (School of Food and Nutrition, Chonju Kijeon Woman's College) ;
  • Kwon, Jin (Korea and Department of Food and Nutrition, So Hae College)
  • 서정숙 (전주기전여자대학 식품.영양계열) ;
  • 권진 (서해대학 식품영양과)
  • Published : 2001.04.01
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Abstract

Immunoregulative action of 70% ethyl alcohol fraction of Cervus nippon was investigated in vitro. The fraction enhanced the proliferation of thymocytes and the population of CD4$\^$+/CD8$\^$-/ single-positive cells in thymocytes. CN-E enhanced [Ca$\^$2+]$\sub$i/, the production of TNF-${\alpha}$ and IL-1 ${\beta}$, and phagocytosis in peritoneal macrophages. The fraction did not induce the proliferation of splenocytes and DNA fragmentation in thymocytes. These results indicate that 70% ethyl alcohol fraction of Cervus nippon regulates immunological action by stimulating murine thymocytes and macrophages.

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