Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Effects of Auricular Acupuncture on NADPH-diaphorase Neurons in Brain Cortex of Fasted Rats

이침자극(耳鍼刺戟)이 절식(絶食) Stress로 인(因)한 흰쥐 대뇌피질(大腦皮質)의 NADPH-diaphorase 신경세포(神經細胞)에 미치는 영향(影響)

  • Lee, Jung-hyun (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Se-Myung University) ;
  • Kim, Ee-Hwa (Department of Meridianology, College of Oriental Medicine, Se-Myung University) ;
  • Lee, Eun-yong (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Se-Myung University)
  • 이정현 (세명대학교 한의과대학 침구학교실) ;
  • 김이화 (세명대학교 한의과대학 경혈학교실) ;
  • 이은용 (세명대학교 한의과대학 침구학교실)
  • Received : 2001.03.05
  • Accepted : 2001.03.20
  • Published : 2001.04.20
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Abstract

Objective : The aim of the present study is to investigate whether stimulating a specific auricular point(胃點) is effect on suppression of appetite. Methods : This study evaluated the changes of Reduced-Nicotinamide-Adenine-inucieotide-Phosphate-diaphorase(NADPH-d)-positive neurons using a histoehemical method. Staining intensities of NADPH-d-positive neurons were assessed in a quantitative fashion using a microdensitometrical method based on optical density by means of an image analyzer. Results : The results show as follows ; 1. In the RSG/RSA, FRI/FR2, HL, PAR1 area, The optical density of NADPH-d-positive neurons of fasted group was significantly decreased in comparison to fed group. 2. In most cortical area, It was not significant statistically, But the optical density of NADPH-d-positive neurons of fed with auricular acupuncture group was decreased in comparison to fed group. 3. In most cortical area, It was not significant statistically, But fasted with auricular acupuncture group increased the optical density of NADPH-d-positive neurons comparison to fasted group. Conclusions : We conclude that stimulating the specific auricular points is able to effect on NO(Nitric Oxide)-expression in the brain cortex of sprague dawley rats, The results suggest that auricular acupuncture may be useful for controlling obesity.

Keywords

References

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