Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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An experimental study of Antiallergic activity of Medicinal Acupunture Solution of Acanthopanax senticosus(Rupr. et Maxim.)

자오가피(刺五加皮) 약침액(藥針液)의 항(抗)알러지 효과(效果)에 대한 실험적(實驗的) 연구(硏究)

  • Yoon, Jong-Tae (Department of Meridian, College of Oriental Medicine, Dae Jeon University) ;
  • Seol, In-Chan (Department of Oriental Internal Medicine, College of Oriental Medicine, Dae Jeon University) ;
  • Kim, Dong-Hee (Department of Oriental Pathology, College of Oriental Medicine, Dae Jeon University) ;
  • Kim, Sung-Hoon (Department of Onocology, Graduate School of East-West Medicine, Kyung Hee University) ;
  • Kim, Han-Sung (Department of Meridian, College of Oriental Medicine, Dae Jeon University)
  • 윤종태 (대전대학교 한의과대학 경혈학교실) ;
  • 설인찬 (대전대학교 한의과대학 심계내과학교실) ;
  • 김동희 (대전대학교 한의과대학 병리학교실) ;
  • 김성훈 (경희대학교 동서의학대학원 종양연구팀) ;
  • 김한성 (대전대학교 한의과대학 경혈학교실)
  • Received : 2001.03.08
  • Accepted : 2001.03.22
  • Published : 2001.04.20
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Abstract

Objetives : This study was done to evaluate the antiallegic effect of medicinal acupuncture solution of Acanthopanax senticosus(Rupr. et Maxim;abbreviated as ASMA), studies were done experimentally. Methods : For this aim MTT assay, anaphylaxis reaction, DTH, histamine release, IgE production and vascular permability was evaluated. Results : ASMA didn't show an effective cytotoxicity on the mouse lung fibroblast. It insignifcantly suppressed histamine release from mast cells induced by compound 48/80, while it significantly reduced IgE production and SRBC-challenged DTH(Delayed type hypersensitivity). ASMA effectively suppressed anaphylactic reaction induced by compound 48/80. However, it didn't inhibit vascular permeability and contact dermatitis significantly. Conclusion:Medicinal acupucture solution had antialletgic effects. Acanthopanax senticosus medical acupuncture depress the allergy reaction. Especially in anaphylactic type, the effect was good.

Keywords

Acknowledgement

Supported by : 보건복지부

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