Effects of Acupuncture on Lipid Composition in Rat Fed High Fat Diet

침자극(鍼刺戟)이 고지방식이(高脂肪食餌)를 급여(給與)한 흰쥐의 체지질구성(體脂質構成)에 미치는 영향(影響)

  • Oh Se-Woong (Dept. of AM-Meridian & Pointology, College of Oriental Medicine, Sangji University) ;
  • Lee Eun (Dept. of Nutrition and Bioresources, Sangji University) ;
  • Lee Joon-Moo (Dept. of AM-Meridian & Pointology, College of Oriental Medicine, Sangji University)
  • 오세웅 (상지대학교 한의과대학 경혈학교실) ;
  • 이은 (상지대학교 생명자원과학대학 영양자원학과) ;
  • 이준무 (상지대학교 한의과대학 경혈학교실)
  • Published : 2001.03.27

Abstract

Effects of $LR_3$(太衝), $GB_{39}$(懸鍾) and $SP_4$(公孫) acupuncture on lipid composition were investigated in rat fed high fat diet. The results obtained from this study are as follows : 1. In the all treatment groups, the body weight values after feeding the basal diet for 4 weeks were significantly decreased compared to the initial body weight. However the decrement of body weight showed a high in acupuncture groups compared to those of control group. In the acupuncture groups, the decrement of body weight showed a high in the $LR_3$ acupuncture groups. 2. The contents of plasma ${\beta}$-lipoprotein and free fatty acids showed a tendency to decrease in the acupuncture groups compared to those of control group and the values of $LR_3$ acupuncture groups showed a low in the acupuncture groups. 3. The contents of plasma triglyceride showed a low values in the complex treatment group of $LR_3,\;GB_{39}$ and $SP_4$. However among the other treatment groups, this values showed no significantly different. The contents of liver triglyceride showed a tendency to decrease in all acupuncture groups except to the complex treatment group of $GB_{39}$ and $SP_4$ acupuncture and in the acupuncture groups, $LR_3$ acupuncture groups were lower than $GB_{39}$ and $SP_4$ acupuncture groups. 4. The contents of plasma glucose showed a tendency to decrease by the acupuncture treatment and $LR_3$ acupuncture groups showed a lower values than other acupuncture groups. 5. In the values of plasma glutamic oxaloacetate transferase activity, $LR_3$ acupuncture group and the complex treatment group of $LR_3,\;GB_{39}$ and $SP_4$ acupuncture were a lower values than other treatment groups and among the other treatment groups showed no significantly different. The values of plasma glutamic pyruvate transferase activity showed no significantly different among all the treatment groups. 6. Contents of plasma and liver total cholesterol showed a tendency to decrease in $LR_3$ acupuncture groups. However those of the other groups showed no significantly different. 7. In the contents of plasma LDL-cholesterol, $LR_3$ acupuncture groups were a lower values than other groups, however among the other groups showed no significantly different. The contents of plasma HDL-cholesterol showed a tendency to increase in the acupuncture groups, however these values showed no significantly different.

Keywords

References

  1. Int. J. Obes. Relat. Metab. Disord. v.16 no.5 Development of dietary dbesity in rats ; influence of amount and composition of dietary fat Hill JO;Lin D;Yakybu F;Peters JC.
  2. FASEB. J. v.8 no.3 Appetite and the regulation of body composition Weigle DS.
  3. Int. J. Obes. Relat. Metab. Disord. v.4 no.Sup.16 Obesity increase risk for diabetes Bray GA.
  4. Am. J. Epidemiol. v.128 no.3 Dietary epidemiology of cancer of the colon in western New York Graham S;Marshall J;Haughey B;Mittelman A;Swanson M;Zielezeny M;Byers T;Wilkinson G;West D.
  5. Int. J. Cancer. v.26 no.6 A case-control study of diet and colo-rectal cancer Jain M;Cook GM;Davis FG;Grace MG;Howe GR;Miller AB.
  6. Stroke v.29 no.5 Dietary vitamin E levels affect outcome of permanent focal cerebral ischemia in rat Van der Worp HB;Bar PR;Kapplle LJ;de Wildt DJ.
  7. Proc. Natl. Acad. Sci. USA. v.94 no.6 Obesity increase sensitivity to endotoin liver injury ; implications for the pathogenesis of steatohepatitis Yang SQ;Lin HZ;Lane MD;Clemens M;Diehi AM.
  8. Circulation v.98 Obesity ; Impact on cardiovascular disease Ronald M. Krauss;Mary W.
  9. Circulation v.97 American heart association call to action ; Obesity as a major risk factor for coronary heart disease Robert HE;Ronald M. Krauss
  10. J. Nutr. v.128 Childhood weight after adult morbidity and mortality William HD.
  11. Curr. Opin. Lipidol. v.8 no.4 Obesity and cardivascular disease is body structure a factor Nielsen S;Jensen MD.
  12. Diabetologia. v.12 no.6 Role of insulin resistance in adipose tissue and liver in the pathogenesis of endogenous hypertriglyceridaemia in man Kissebah AH;Alfarsi S;Adams PW;Wynn V.
  13. Diabetologia. v.31 no.5 Artificial induction of intravascular lipolysis by lipid-heparin infusion leads to insulin resistance in man Lee KU;Lee HK;Koh CS;Min HK.
  14. 第2次全國中西醫結合 肥滿病硏究學術論文的要偏 600例 單純性肥滿患者與中醫分型的關係 申署謹
  15. 中醫雜誌 v.28 輕身飮Ⅱ號 治療單純性肥滿病46例臨床療效觀察 康延培
  16. 北京中醫 從肝論治單純性肥滿病40例臨床觀察 曲竹秋
  17. 中醫雜誌 v.27 減肥驗案4則 王玉芬
  18. 協書中醫 v.4 耳穴點壓感肥500例 楊金榮
  19. 貴州醫藥 v.10 no.5 耳穴按壓法感肥 1000例臨床療效報道 呂明壓
  20. 協書中醫 v.7 耳穴點壓治療肥滿症200例療效觀察 殷榮亮
  21. 中國鍼灸 v.6 耳穴坤鍼感肥253例臨床觀察 李士杰
  22. 按摩與圖 按摩治療肥滿症21例效果觀察 吳繼武
  23. 中醫雜誌 v.30 耳鍼減肥110例臨床觀察 張忠志
  24. 中醫藥新式 耳鍼治療肥滿550例療效分析 崔述貴
  25. Lakartidningen. v.84 no.38 Awarning against ear acupuncture used in the treatment of obesity Dahlqvist A.;Johnsen J.
  26. Ter Arkh. v.57 no.10 Role of reflexotherapy in the complex treatment of neuroendocrine obesity MV.;Bogdanovich VL.
  27. 第2次全國中西醫結合肥滿病硏究學術論文的要編 鍼灸對單純性肥滿患者糖代謝的影響 趙銀龍
  28. 第2次全國中西醫結合肥滿病硏究學術論文的要編 鍼灸對單純肥滿病發高血壓患者的調整作用 劉志誠
  29. 上海鍼灸雜誌 耳穴坤壓治療肥滿症 568例臨床觀察 劉抗華
  30. 四川中醫 v.5 耳壓治療肥滿症50例小結 王聲芳
  31. 中國鍼灸 v.10 耳鍼對靑年男女體型的影響 張忠志
  32. 中國鍼灸 v.4 坤耳鍼減肥350例療效觀察 徐彬
  33. 上海鍼灸雜誌 v.7 鍼刺減肥300例療效分析 李凝凜
  34. 第2次中國中西醫結合肥滿病硏究學術論文要的編 肥滿的中醫治療 原桃仁
  35. 中醫雜誌 v.29 從肝論治單純性肥滿病40例臨床觀察 曲竹秋
  36. 上海中醫藥雜誌 大黃片治療超重症500例 화보분
  37. 四川中醫 v.6 耳穴點壓加防風通聖丸治療肥滿症147例 孫廣培
  38. 中醫雜誌 鍼灸配合治療單純性肥滿95例臨床觀察 陳瑞榮
  39. 中西醫結合雜誌 v.11 從植物神經功能和血漿環核減酸含量的變化觀察鍼灸減肥作用 劉志誠
  40. 江蘇中醫 v.12 鍼灸減肥342例臨床觀察 胡萌梅
  41. 氣功科學 香能功配耳壓按摩法減肥2980例 淳于家平
  42. 鍼灸學(上) 崔容泰(外)
  43. 經穴學叢書 安榮基
  44. 東洋醫學 v.13 艾久生體反應의 文獻的 考察 林鍾國
  45. 最新醫學 v.52 no.6 脂肪細胞における脂肪の分解と合成 奧田拓道
  46. 한국영양학회지 v.32 no.4 감잎, 녹차, 솔잎의 건분 및 에타놀추출물이 흰쥐의 지방대사와 항산화능에 미치는 영향 김은성;김미경
  47. Korean J Nutrition. v.28 no.1 Effects of aqueous green tea extracts with ${\alpha}$-tocopherol and lecithin on the lipid metabolism in serum and liver of rats Chung, CH;Yoo Ys.
  48. J Korean Soc Food Nutr. v.25 no.3 Effects of pine needle extracts on serum and liver lipid contents in rats fed high fat diet Kang YH;Park YK;Ha TY;Moon KD.
  49. Bulletin of Food Technology v.10 no.2 The protect the living organ from free radicals and the failure of protection ; age-related disease Kim YJ.
  50. Phytochemistry v.26 no.9 Hydropxyl radical scavenging activity of flavonoids Husain SR;Cillard J;Cillard P.
  51. Phytochemistry v.25 no.2 Antioxidant activity of flavonoids and reactivity with peroxyl radical Torel J;Cillard J;Cillard P.
  52. 한국영양학회지 v.32 no.4 한국고유의 산채류첨가식이가 흰쥐의 지방대사 및 항산화능과 카드뮴제독에 미치는 영향 박진아;김미경
  53. 한국영양학회지 v.28 no.1 녹차 물 추출물에 토코페롤과 레시틴첨가가 흰쥐의 혈장과 간의 지질대상에 미치는 영향 정희정;유영상
  54. 한국영양학회지 v.32 no.5 깻잎, 쑥, 참취의 건분 및 에타놀추출물이 흰쥐의 지방대사와 항산화능에 미치는 영향 김주희;김미경
  55. 한국식품과학회지 v.20 no.1 영지, 케일 및 Sodium dextrothyroxine이 고콜레스테롤 혈증 흰쥐의 지질대상에 미치는 영향 정승용;김승희
  56. 한국영양식량학회지 v.21 no.1 오갈피의 열수추출액이 고지방식이에 의한 비만유도 흰쥐의 지방축적에 미치는 영향 성태수;손규목;배만종;최청
  57. 생약학회지 v.23 no.3 고들빼기의 고콜레스테롤혈증 개선효과 양한석;최재수;이지현
  58. 한국식품과학회지 v.32 no.5 솔잎분말이 고콜레스테롤급여 흰쥐의 체지질구성과 TBARS량에 미치는 영향 이은;최무영
  59. Life Sci. Research Ins. Effects of Green tea on serum lipid composition and TBARS in chicks with oxidized lipid Lee, E.
  60. 한국영양학회지 v.33 no.5 시호분말이 과산화지질을 급여한 흰쥐의 혈장 및 간장지질구성에 미치는 영향 이은;최무영;오혜숙
  61. Kor. J. Pharmacogn. v.28 Serum cholesterollowering effect of triterpene acetate obtained from Latuca indica Kim, MJ.;Lee, E.;Cha, B.C.;Choi, M.Y.;Rhim, T.J.;Park, H.J.
  62. J. Korean Soc. Food Sci. Nutr. v.28 Effects of rhus chinensis gall extract on liver function, plasma lipid composition and antioxidant system in rats with high fat diet Choi, M.Y.;Cho, E.J.;Lee, E.
  63. 한국영양학회지 v.32 no.3 타우린과 베타알라딘이 실험적 당뇨유발쥐의 혈당 및 혈중지질농도에 미치는 영향 장경자
  64. 한국영양학회지 v.32 no.2 올리고당 첨가식이가 흰쥐의 지질대사에 미치는 영향 오선진;김우경;김양하;김혜경;최은혜;김숙희
  65. 한국영양학회지 v.32 no.5 영지가 알코올섭취한 흰쥐의 간기능 및 지질대사에 미치는 영향 이준희;박광순
  66. 한국영양학회지 v.32 no.6 두류의 첨가가 당뇨병쥐의 장기능과 당뇨증세에 미치는 영향 박수현;이혜성
  67. Diabetes Educator v.9 The nutritonal therapy of non-insulin dependent (type Ⅱ) diabetes Anderson JW.
  68. Anim. Sci. J. v.71 no.4 Growth-depressing and cholesterol-lowering effects of quillaja and tea saponins in chicks as influenced by diet composition Ueda, H.;Tanoue, K.
  69. 한국영양식량학회지 v.18 no.1 콜레스테롤식이로 사육한 흰쥐의 혈장 및 간지질성분에 미치는 카페인 및 비타민 E의 영향 조수열;박미리;박원학;정재홍
  70. 痰飮淺說 宗文九
  71. 대한한의학회지 v.12 no.1 防風通聖散이 고혈압, 고지혈에 미치는 영향 李南勳;李京燮
  72. 대전대학교석사학위논문 淸肝湯이 고지혈증에 미치는 영향 孫彰奎
  73. 대전대학교석사학위논문 半夏白朮天麻湯이 고지혈증에 미치는 영향 崔淳暾
  74. 대한한방내과학회지 v.12 고혈압 및 고지혈증에 대한 淸熱導痰湯의 실험적 연구 李大植
  75. 遼寧中醫雜誌 v.12 no.1 人蔘降脂合濟的臨床及動物實驗硏究 陳湘君
  76. 中醫雜誌 v.32 no.12 통어운령치료당뇨병고지혈증적임상화학실험연구 朱良爭
  77. 新中醫 v.22 no.8 加味桃核承氣湯對糖尿病對大鼠脂質代謝的影響 張國梁;能漫琪
  78. 동국대학교 박사학위논문 혈전증과 打撲性 充血 및 高脂血症에 順氣導痰湯 및 化瘀湯이 미치는 影響 朴元煥
  79. 대한동의병리학회지 v.2 血府遂瘀湯이 혈전증과 피하혈종에 미치는 영향 崔承勳
  80. 대한동의병리학회지 v.3 黃帝內經에서의 어혈의 인식에 대한 이론적 연구 崔承勳
  81. Am J Clin Nutr. v.66 no.2 Effect of tea flavonoid supplementation on the susceptibility of low-density lipoprotein to oxidative modification Ishikawa, T;Suzukawa M.
  82. Diabetes v.30 no.Sup.2 Cholesterol metabolism in diabetes mellitus Saudek CD;Young, NL.
  83. 임상생화학 김종호