Journal of Pharmaceutical Investigation
- Volume 31 Issue 1
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- Pages.27-35
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- 2001
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Permeation and Enzymatic Degradation of Aspalatone in Gastrointestinal Tract of Rabbit
아스팔라톤의 토끼 위장관 점막 투과 및 효소적 분해
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Chun, In-Koo
(College of Pharmacy, Dongduk Women's University) ;
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Gwak, Hye-Sun
(College or Pharmacy, Dongduk Women's University)
- Published : 2001.03.20
Abstract
To evaluate the site-specific permeation of aspalatone (acetylsalicylic acid maltol ester, AM) through gastrointestinal tract, the enzymatic degradation and permeation studies were carried out using gastric, duodenal and jejunal mucosae of rabbits. It was found that
Keywords
- Aspalatone;
- Aspirin;
- Permeation;
- Gastrointestinal Mucosa;
- Enzymatic degradation;
- Potassium fluoride;
- Cyclodextrins