생약학회지 (Korean Journal of Pharmacognosy)
- 제32권4호통권127호
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- Pages.257-268
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- 2001
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
빈용 한약재의 진통 소염활성
Analgesic and Antiinflammatory Activities of Some Oriental Herbal Medicines
- 박종은 (경희대학교 동서의학연구소) ;
-
최혁재
(경희대학교 동서의학연구소)
;
-
정석희
(경희대학교 한의과대학)
;
-
김동현
(경희대학교 약학대학)
;
-
김남재
(경희대학교 동서의학연구소)
- Park, Jong-Eun (East-West Medical Research Institute, Kyung Hee University) ;
-
Choi, Hyuk-Jae
(East-West Medical Research Institute, Kyung Hee University)
;
-
Jung, Suk-Hee
(College of Oriental Medicine, Kyung Hee University)
;
-
Kim, Dong-Hyun
(College of Pharmacy, Kyung Hee University)
;
-
Kim, Nam-Jae
(East-West Medical Research Institute, Kyung Hee University)
- 발행 : 2001.12.30
초록
Analgesic and antiinflammatory activities of several herbal medicines were investigated in order to develop the antiinflammatory drugs from oriental herbal medicines. 80% Ethanol extracts of Ephedra sinica, Chaenoleles sinensis, Asiasarum siboldi, Nelumbo nucifera, Scolopendra subspinipes mutians, Evodia officinalis, Aremarrhenae asphodeloides, Bufo bufo gargarizans, Gardenia jasminoides, Piper longum, Carthamus tinctorius, Piperus nigrum, Magnolia officinalis and Siegesbeckia glabrescens showed significant inhibitory effects on hyaluronidase, trypsin, and albumin denaturation in vitro. They also decreased the acetic acid-induced pain and vascular permeability induced by histamine in mice.