Screening on Biological Activities of the Extracts from Fruit and Stem of Prickly Pear(Opuntia ficus-indica var. saboten)

손바닥 선인장 열매 및 줄기 추출물의 생리활성(I)-일반약리검색

  • 이정규 (경성대학교 약학대학) ;
  • 이영철 (한국식품개발연구원 농산물이용연구부) ;
  • 문영인 (북제주군 농업기술센터) ;
  • 박희준 (상지대학교 응용식물과학부) ;
  • 한용남 (서울대학교 천연물과학연구소) ;
  • 최종원 (경성대학교 약학대학)
  • Published : 2001.12.30

Abstract

Prickly pear(Opuntia ficus-indica var. saboten Makino, Cactaceae) is a tropical or subtropical plant, which is widely used as folk medicine for burned wound, edema and indigestion. Screening on the biological properties of the fruits(OFS-Fr) and stems(OFS-St) of the plant was carried out to prove the pharmacological significance. By hot plate and acetic acid-inducing writhing methods, significant analgesic effects of OFS-Fr and OFS-St were found in mice and anti-edemic effect was observed in carrageenin-induced inflammatory rats. However, the extracts showed no significant actions on central and autonomic nervous system and blood circulatory system, which imply no toxic effects to animal.

Keywords