Korean Journal of Pharmacognosy (생약학회지)
- Volume 32 Issue 3 Serial No. 126
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- Pages.212-218
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- 2001
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Binding affinity of some herbal extracts on the glycine binding site of NMDA (N-Methyl-D-Aspartate) receptor
수종 생약추출물의 NMDA(N-Methyl-D-Aspartate) 수용체 glycine binding site에 대한 친화력 검색
-
Kim, Young-Sup
(Bio-Organic Science Division, Korea Research Institute of Chemical Technology)
;
- Kim, Jeoung-Seob (Bio-Organic Science Division, Korea Research Institute of Chemical Technology) ;
- Kim, Seong-Kie (Bio-Organic Science Division, Korea Research Institute of Chemical Technology) ;
- Heor, Jung-Hee (Bio-Organic Science Division, Korea Research Institute of Chemical Technology) ;
-
Lee, Byung-Eui
(Bio-Organic Science Division, Korea Research Institute of Chemical Technology)
;
-
Ryu, Shi-Yong
(Bio-Organic Science Division, Korea Research Institute of Chemical Technology)
-
김영섭
(한국화학연구원 화학물질연구부)
;
- 김정섭 (한국화학연구원 화학물질연구부) ;
- 김성기 (한국화학연구원 화학물질연구부) ;
- 허정희 (한국화학연구원 화학물질연구부) ;
-
이병의
(한국화학연구원 화학물질연구부)
;
-
유시용
(한국화학연구원 화학물질연구부)
- Published : 2001.09.30
Abstract
The water extracts of 82 Korean medicinal herbs were prepared and were examined for the binding affinity on the glycine binding site of NMDA (N-methyl-D-aspartate) receptor prepared by the synaptic membranes from the forebrains of male Sprague-Dawley rats. Among the tested, the extracts of Dioscoreae Rhizoma, Hoveniae Semen cum Fructus, Astragali Radix, Armeniacae Semen, Huttuynia cordata Herba, Acanthopanacis Cortex, Aurantii nobilis Pericarpium, Phellinus linteus, Amomi Fructus, Artemisiae capillaris Herba, Polyporus, Agastachis Herba and of Galli Stomachichum Corium were found to exhibit significant competitions with