Korean Journal of Pharmacognosy (생약학회지)
- Volume 32 Issue 2 Serial No. 125
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- Pages.153-156
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- 2001
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Isolation and Quantitative Determination of Dioscin from Smilacis Chinae Radix
토복령(土茯令, Smilacis Chinae Radix)으로부터 Dioscin의 분리 및 함량분석
- Seo, Jung-Hak (Department of Food and Nutrition, Andong National University) ;
- Lee, Joo-Mi (Department of Food and Nutrition, Andong National University) ;
- Kwon, Soon-Jin (Department of Food and Nutrition, Andong National University) ;
- Chang, Seung-Yeup (Korea Food and Drug Administration) ;
- Lee, Kyong-Soon (College of Pharmacy, Chungbuk National University) ;
- Son, Kun-Ho (Department of Food and Nutrition, Andong National University)
- 서정학 (안동대학교 식품영양학과) ;
- 이주미 (안동대학교 식품영양학과) ;
- 권순진 (안동대학교 식품영양학과) ;
- 장승엽 (식품의약품안전청) ;
- 이경순 (충북대학교 약학대학) ;
- 손건호 (안동대학교 식품영양학과)
- Published : 2001.06.30
Abstract
The methods for isolation and quantitative determination of dioscin, a spirostanol triglycoside, from the roots of Smilax china have been developed. Isolation of dioscin was achieved by silica gel and RP-18 chromatography. The HPLC method used for quantitative determination of dioscin enabled the standardization of the crude drug. It suggests that the content of dioscin in Smilax china should be above 0.01%.