BMB Reports
- 제33권1호
- /
- Pages.75-81
- /
- 2000
- /
- 1976-670X(eISSN)
Characterization of dnaK Mutants in Streptococcus pneumoniae
- Kim, Seung-Whan (College of Pharmacy, Sungkyunkwan University) ;
- Pyo, Suhk-Neung (College of Pharmacy, Sungkyunkwan University) ;
- Rhee, Dong-Kwon (College of Pharmacy, Sungkyunkwan University)
- 투고 : 1999.09.17
- 심사 : 1999.11.09
- 발행 : 2000.01.31
초록
DnaK is a major heat shock protein and known to be highly conserved in all species. Previously, the dnaK in Streptococcus pneumoniae was cloned and the immunogenic nature characterized. In this study, dnaK mutants were generated by insertion of duplication mutagenesis and their characteristics examined. They had defective growths at all temperatures (