The Korean Journal of Pain
- Volume 13 Issue 2
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- Pages.149-155
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- 2000
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- 2005-9159(pISSN)
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- 2093-0569(eISSN)
The Analgesic Effect and Its Neuropathologic Changes of Pulsed Radiofrequency Lesions in the Sciatic Nerve of the Rat
백서 좌골신경에 시행한 박동성 고주파술 (Pulsed Radiofrequency)이 급성 통증과 신경조직에 미치는 영향
- Lee, Kee-Heon (Department of Anesthesiology, College of Medicine, Hallym University) ;
- Shin, Keun-Man (Department of Anesthesiology, College of Medicine, Hallym University) ;
- Kweon, Kyoung-Seok (Department of Anesthesiology, College of Medicine, Hallym University) ;
- Jung, Bae-Hee (Department of Anesthesiology, College of Medicine, Hallym University) ;
- Lim, So-Young (Department of Anesthesiology, College of Medicine, Hallym University) ;
- Hong, Soon-Yong (Department of Anesthesiology, College of Medicine, Hallym University) ;
- Choi, Young-Hee (Department of Pathology, College of Medicine, Hallym University) ;
- Park, Young-Euy (Department of Pathology, College of Medicine, Hallym University)
- 이기헌 (한림대학교 의과대학 마취과학교실) ;
- 신근만 (한림대학교 의과대학 마취과학교실) ;
- 권경석 (한림대학교 의과대학 마취과학교실) ;
- 정배희 (한림대학교 의과대학 마취과학교실) ;
- 임소영 (한림대학교 의과대학 마취과학교실) ;
- 홍순용 (한림대학교 의과대학 마취과학교실) ;
- 최영희 (한림대학교 의과대학 병리학교실) ;
- 박영의 (한림대학교 의과대학 병리학교실)
- Published : 2000.11.30
Abstract
Background: Pulsed radiofrequency (RF) lesioning is a painless procedure and causes no neurodestruction and neuritis-like reaction are common following conventional RF lesioning. There is little data about the effect of pulsed RF especially with regard to its suitability for the treatment of acute pain. The possibility of a placebo effect cannot be ruled out because a double-blind study was not performed in previous studies. There is also no neuropathologic study about pulsed RF. Methods: The rats were anesthetized with sodium pentobarbital (40 mg/kg, i.p.; supplemented as necessary). The common sciatic nerve was exposed by blunt dissection through biceps femoris. Pulsed RF was administered to the common sciatic nerve using a 30 ms/s pulse with for 120 seconds. The temperature reached was no more than
Keywords
- Pain: acute;
- Research: hot-plate test;
- neuropathologic changes;
- Surgery: pulsed radiofrequency lesion