Efficacy of Gabapentin Monotherapy on the Neuropathic Pain -Case report-

신경병증성 통증환자에서 Gabapentin 단일 요법의 효과 -증례 보고-

  • Kim, Woo-Sun (Department of Anesthesiology, Chonbuk National University Medical School) ;
  • Han, Young-Jin (Department of Anesthesiology, Chonbuk National University Medical School) ;
  • Choe, Huhn (Department of Anesthesiology, Chonbuk National University Medical School)
  • 김우선 (전북대학교 의과대학 마취과학교실) ;
  • 한영진 (전북대학교 의과대학 마취과학교실) ;
  • 최훈 (전북대학교 의과대학 마취과학교실)
  • Published : 2000.06.30

Abstract

Since conventional analgesics have showed limited therapertic value in the treatment of painful neuropathy, the new anticonvulsant gabapentin, has been tried and turned out to be effective and safe in the treatment for various forms of neuropathic pain. The basic pathophysiology of neuropathic pains is abnormal neuronal hyperactivity similar to epileptic seizures. Therefore, we could expect that neuropathic pain would be suppressed by anticonvulsants which inhibit abnormal excessive neuronal output and nerve conduction. This report include effective pain relief in four cases of neuropathic pain with gabapentin without any significant complications.

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