Korean Journal of Veterinary Research (대한수의학회지)
- Volume 40 Issue 4
- /
- Pages.741-746
- /
- 2000
- /
- 2466-1384(pISSN)
- /
- 2466-1392(eISSN)
Determination of new anti-HIV agents, the KR-V series, in rat plasma using microbore high-performance liquid chromatography
HPLC를 이용한 랫드혈장내 새로운 항HIV제 KR-V series의 분석법
- Lee, Young-mi (Department of Pharmacokinetics & Toxicokinetics, Korea Research Institute of Chemical Technology) ;
- Park, Myung-jin (Department of Pharmacokinetics & Toxicokinetics, Korea Research Institute of Chemical Technology) ;
- Kim, Jin-suk (College of Veterinary Medicine, Konkuk University, Korea) ;
- Shin, Ho-chul (Department of Pharmacokinetics & Toxicokinetics, Korea Research Institute of Chemical Technology)
- Accepted : 2000.09.06
- Published : 2000.12.20
Abstract
We have developed a rapid, simple and precise high-performance liquid chromatographic (HPLC) method using an UV detection system for the determination of new anti-HIV candidates, nineteen KR-V compounds, in rat plasma. We used a analytical columnn of
최근 새로 개발중인 항AIDS치료제 KR-V 시리즈를 대상으로 HPLC-UV 검출법을 이용해 랫드 혈장중에서 분석법을 검토하였다. 분석컬럼은