A Case of Pellagra with Zinc Deficiency

아연 결핍증에 동반된 Pellagra 1례

  • Oh, Ha-Na (Department of Pediatrics, College of Medicine, Yonsei University) ;
  • Yoo, Jee-Hyung (Department of Pediatrics, College of Medicine, Yonsei University) ;
  • Lee, Chang-Han (Department of Pediatrics, Pundang CHA Hospital, College of Medicine, Pochon CHA University) ;
  • Chung, Ki-Sup (Department of Pediatrics, College of Medicine, Yonsei University)
  • 오하나 (연세의대 소아과학교실) ;
  • 유지형 (연세의대 소아과학교실) ;
  • 이창한 (포천중문의대 소아과학교실) ;
  • 정기섭 (연세의대 소아과학교실)
  • Received : 2000.09.05
  • Accepted : 2000.09.20
  • Published : 2000.09.30

Abstract

Pellagra is a systemic disease associated with neuropathy, caused by dietary insufficiency of nicotinic acid and it's precursor, tryptophan, which are vital to the function of cellular dehydrogenases in tissue respiration. Clinical triads are dermatitis, dementia, and diarrhea. The authors experienced a case of pellagra in 5-year old girl. She had a history of acrodermatitis enteropathica, three years ago. Erythematous scaly patches and hyperpigmentation developed on her great toes, bilaterally. Diarriea and ataxic gait were also noted. After vitamin B complex with nicotinamide therapy, diarrhea and dermatitis were dramatically improved within a few days, and ataxic gait was gradually improved.

저자들은 2세경 아연결핍증을 진단받고 외래 추적관찰 중이던 5세된 여아에서 피부염, 설사, 신경증상 등을 보이는 전형적인 pellagra 1례를 경험하였기에 이에 보고하는 바이다.

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