Pediatric Gastroenterology, Hepatology & Nutrition
- Volume 3 Issue 1
- /
- Pages.105-109
- /
- 2000
- /
- 2234-8646(pISSN)
- /
- 2234-8840(eISSN)
Hepatocellular Carcinoma Following Vertical Transmission of Hepatitis B Virus in a Child with X-linked Agammaglobulinemia
범저감마 글로불린혈증 환아에서 B형 간염 바이러스 수직 감염에 의해 발생한 간세포 암종 1례
- Oh, Jong-Gon (Department of Pediatrics, St. Columban's Hospital) ;
- Kim, Byung-Ju (Department of Pediatrics, Chonnam National University Medical School) ;
- Kook, Hoon (Department of Pediatrics, Chonnam National University Medical School) ;
- Woo, Young-Jong (Department of Pediatrics, Chonnam National University Medical School) ;
- Choi, Young-Youn (Department of Pediatrics, Chonnam National University Medical School) ;
- Ma, Jae-Sook (Department of Pediatrics, Chonnam National University Medical School) ;
-
Hwang, Tai-Ju
(Department of Pediatrics, Chonnam National University Medical School)
;
- Seo, Jong-Jin (Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center)
- 오종곤 (성골롬반병원 소아과) ;
- 김병주 (전남대학교 의과대학 소아과학교실) ;
- 국훈 (전남대학교 의과대학 소아과학교실) ;
- 우영종 (전남대학교 의과대학 소아과학교실) ;
- 최영륜 (전남대학교 의과대학 소아과학교실) ;
- 마재숙 (전남대학교 의과대학 소아과학교실) ;
-
황태주
(전남대학교 의과대학 소아과학교실)
;
- 서종진 (울산대학교 의과대학 소아과학교실)
- Received : 1999.12.30
- Accepted : 2000.02.18
- Published : 2000.03.30
Abstract
X-linked agammaglobulinemia (XLA) is a primary inherited B-cell immunodeficiency. The prevalence of neoplastic disease in patients with XLA is approximatedly 0.7%. The most frequent tumor is lymphoreticular malignancy. We report a case of hepatocellular carcinoma (HCC) in a 13-year-old boy with XLA, after probable maternal transmission of hepatitis B virus. The authors consider that the vertical transmission of hepatitis B virus might play an important role in the development of HCC in a child with XLA who could not eliminate hepatitis B virus effectively.
저자들은 B형 간염 바이러스에 수직 감염된 13세 된 XLA 환아에서 발생한 간세포 암종 1례를 경험하였기에 보고하는 바이며, 간세포 암종의 발생은 XLA 환아에서 수직 감염된 B형 간염 바이러스가 효과적으로 제거되지 못해 발생되었을 것으로 사료된다.