Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Pain Control Effects of $Myprodol^{(R)}$ after Periodontal Surgery and Dental Implant Surgery

치주 수술 및 인공 치아 매식술 후 $Myprodol^{(R)}$의 동통 억제 효과에 대한 연구

  • Cho, Kyoo-Sung (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration) ;
  • Lee, Jung-Hoon (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration) ;
  • Kim, Hyun-Young (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration) ;
  • Suh, Jong-Gin (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration) ;
  • Choi, Seong-Ho (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration) ;
  • Chai, Jung-Kiu (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration) ;
  • Kim, Chong-Kwan (Department of Periodontology, College of Dentistry, Yonsei University, Research Institutes for Periodontal Tissue Regeneration)
  • 조규성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 이정훈 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김현영 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 서종진 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 최성호 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 채중규 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김종관 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소)
  • Published : 2000.03.30
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Abstract

Although various analgesics have been administrated for postoperative pain control, postoperative pain has not been adequately controlled . The purpose of this study was to evaluate the effects and patient's satisfaction of $Myprodol^{(R)}$(combination analgesics with codeine, ibuprofen, paracetamol) compared to Acetamionphen and placebo drug after periodontal surgery and dental implant surgery. We studied 98 cases of outpatients which were composed of 67 cases of flap operation(which separated to 3 groups: Placebo group(n=25), $Myprodol^{(R)}$ group(n=22), Acetaminophen group(n=20)) and 21 cases of dental implant surgery(which separated to 3 groups : Placebo group(n=10), $Myprodol^{(R)}$ group(n=12), Acetaminophen group(n=9)). We evaluated the postoperative pain(Pain 1), Pain after first drug administraion(Pain 2), the degrees of pain reduction(pain 3), patient's satisfaction for drug, and side-effects. We obtained following results; 1. In Pain 1, making a comparison among groups, there was no significant difference in both cases of flap operation-group and dental implant surgery-group 2. In Pain 2, establishing a comparison among groups, there was no significant difference in flap operation-group, but significant difference was seen between placebo group and $Myprodol^{(R)}$ group in cases of dental implant surgery group(P<0.05). 3. In Pain 3, making a comparison among groups, $Myprodol^{(R)}$ group showed significant differences compared to placebo group and Acetaminophen group in both cases of flap operation group and dental implant surgery group(P<0.05). 4. In patient's satisfactory score, making a comparison among groups, there were significant differences between placebo group and $Myprodol^{(R)}$ group in cases of flap operation group and between $Myprodol^{(R)}$ group and Acetaminophen group in cases of dental implant surgery group(P<0.05). 5. Making a comparison in side-dffect, no significant differrence was seen. Our conclusion is that $Myprodol^{(R)}$ is a effective oral analgesics to the patients who underwent periodontal surgery or implant surgery for it's synergism among three dugs.

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