The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Fine Needle Aspiration Cytology of Diffuse Sclerosing Variant of Papillary Carcinoma of the Thyroid - A Case Report -

갑상선의 미만성 경화성 변종 유두상 암종의 세침흡인 세포학적 소견 - 1예 보고 -

  • Kim, Joon-Mee (Department Anatomical Pathology, Inha University Hospital) ;
  • Min, Soo-Kee (Department Anatomical Pathology, Inha University Hospital) ;
  • Chu, Young-Chae (Department Anatomical Pathology, Inha University Hospital) ;
  • Kim, Mi-Rim (Department Internal Medicine, Inha University Hospital) ;
  • Kim, Kyung-Rae (Department General Surgery, Inha University Hospital)
  • 김준미 (인하대학교 병원 해부병리과) ;
  • 민수기 (인하대학교 병원 해부병리과) ;
  • 주영채 (인하대학교 병원 해부병리과) ;
  • 김미림 (인하대학교 병원 내과) ;
  • 김경래 (인하대학교 병원 외과)
  • Published : 2000.06.30
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Abstract

Diffuse sclerosing papillary carcinoma(DSPC), a variant of papillary carcinoma of the thyroid, is characterized by diffuse involvement of one or both thyroid lobes, and histologic features such as prominent sclerosis, intense lymphocytic infiltrate, numerous psammoma bodies, and squamous metaplasia together with the characteristic cytoarchitectural pattern of classical papillary carcinoma. We experienced a case of fine needle aspiration cytologic(FNAC) findings of DSPC, which was confirmed by histologic examination of the thyroidectomy specimens. The patient was 26 years old female who presented with diffuse firm enlargement of the thyroid gland with enlargement of many cervical lymph nodes. FNAC smears showed numerous psammoma bodies, many lymphocytes, metaplastic squamous cells, absence of stringy colloid, and epithelial cells showing classical features of papillary carcinoma, such as nuclear grooves, intranuclear unclusions, and ground glass chromatin pattern.

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