The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지

The Effect of Boyanghwano-tang Extracts on Reversible Forebrain Ischemia in Mongolian Gerbil

Mongolian Gerbil의 Reversible Forebrain Ischemia 모델에 미치는 보양환오탕의 효과

  • 최은정 (동국대학교 한의과대학 내과학교실) ;
  • 정승현 (동국대학교 한의과대학 내과학교실) ;
  • 박인식 (동국대학교 한의과대학 해부학교실) ;
  • 신길조 (동국대학교 한의과대학 내과학교실) ;
  • 이원철 (동국대학교 한의과대학 내과학교실)
  • Published : 2000.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : This study was carried out to evaluate the effect of Boyanghwano-tang Extracts on Reversible Forebrain Ischemia in Mongolian Gerbils. Methods : The water content of cerebral edema and the morphologicalㆍneurocytochemistrical change of neuron in MG were implemented to conduct this study. Results : The change rate of water content by ischemia in the normal group was 78.90% on the third day and 79.12% on the seventh day after an attack of ischemia. The rate in the control group was 80.34% and 81.72%. In the sample group the rate was 79.85% and 80.97%. This is a significant result. According to the result of the optical microscopic examination, the cells seen to be continuous and systematic in the pyramidal cells of hippocampus were changed into discontinuous and unsystematic forms in the control group. But compared with the control group, the cells were less damaged in the sample group. Conclusions : The data shows that the effect of Boyanghwano-tang Extracts on Reversible Forebrain Ischemia in MG is a significant result.

Keywords

References

  1. 中西醫結合雜誌 v.13 加減補陽還五湯的抗血栓形成和溶血栓作用 段登志;薛朝霞;陳黎明;鄒蓮芳;공화학;史玉蓉
  2. 中國中西醫結合雜誌 v.12 보양환오탕대실험성뇌수종양자유기여세포초징결구변화적영향 譚峰;歐正武;李安國;李暉;賀石林;虞佩蘭;張寶林;彭隆祥;文幷連
  3. 中醫雜誌 v.6 補陽還五湯治療腦血栓形成的臨床及血液流變學關察 왕행길;周孝達;錢可久
  4. 新中醫 v.8 補陽還五湯治特發性水腫 구강
  5. 사망원인통계연보(인구동태신고에 의한 집계) 경제기획원 조사통계국
  6. 대한신경과학회지 v.16 no.2 Gerbil의 일과성 전뇌허혈모델에서 Lamotrigine에 의한 해마의 지연성 신경세포손상 감소효과 이용석;윤병우;노재규
  7. 임상중풍학 김영석
  8. 한$\cdot$중 중풍병 학술대회 참가 논문집 중풍초기환자에 대한 방풍통성산의 임상적 연구 강화정;황치원
  9. 대한한방내과학회지 v.19 no.1 Funcitonal Independence Measure를 이용한 뇌졸증 환자의 임상적 관찰 김민석;정승현;신길조;이원철
  10. 대한한의학회지 v.15 no.2 졸중풍 후유증에 의한 운동장애 환자의 치료를 위한 通用方으로서 萬金湯과 補陽還五湯의 효과에 관한 비교 연구 김동웅
  11. 醫林改錯 王淸任
  12. 活血化瘀名家王淸任 中國中醫硏究院廣安門醫院
  13. 上海中醫藥雜誌 v.3 補陽還五湯的臨床及實驗硏究進展 王臨江;王佩芳
  14. 中西醫結合雜誌 v.9 補陽還五湯對血管壁抗血栓功能的影響 李安國;賀石林;鄭常靑;彭延古
  15. 河南中醫雜誌 v.11 補陽還五湯降血液粘度臨床64例扱告 何保儀
  16. 福建中醫藥 v.2 補陽還五湯在腦卒中的應用 曹波
  17. 新中醫 v.9 補陽還五湯加味治療無精症7例 王存民
  18. 中醫雜誌 v.10 補陽還五湯治愈小兒偏風1例 劉玉英
  19. Neurochemistry v.43 Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis Benveniste H;Drejer J;Schousboe A;Diemer NH.
  20. Neurosurgery v.33 Beneficial effect of prolonged administration of albumin on ischemic cerebral edema and infartion after occlusion of middle cerebral artery in rats Toru Matsuo;Hiroshi Sinyama;Takao Asano.
  21. J Neurol Neurosurg Psychiatry v.53 The frequency, causes and Timing of Death within 30 Days of a First Stroke: The Oxford-shire Community Stroke Project Bamford J;Dennis M;Sandercock PAG;Burn J;Warlow C.
  22. 대한신경과학회지 v.7 최근 국내 뇌졸증의 역학적 동향에 대한 연구 명호진;이상복;노재규;윤병우;이원용;김명호;김주한;위봉애;정진상;권오상
  23. Progress in Neurobiology v.40 Mechanism and Pathogenesis of ischemia-induced neuronal damage Hideaki Hara;Takayuki Sukamoto;Kyuya Kogure
  24. TiPS. v.17 Emerging treatments for stroke in humans Walter J Koroshetz;Michael A Moskowitz.
  25. J Cereb Blood Flow Metab. v.9 Calcium fluxes, calcium antagonists, and calciumrelated pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis Siesjo BK;Bengtsson F.
  26. J Neurochem. v.43 Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis Benveniste H;Drejer J;Schousboe A;Diemer NS.
  27. Ann Neurol. v.24 The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat Park CK;Nehls DG;Graham DI;Teasdale GM;Mcculloch J.
  28. Neuropharmacology v.26 The interaction between MK-801 and receptors for N-methyl-D-aspartate: functional consequences Woodruff GN;Foster AC;Gill R;Kemp JA;Wong EH;Iversen LL.
  29. Ann Neurol. v.18 Effect of pertreatment with the calcium antagomist nimodipine on local cerebral blood flow and histopathology after middle cerbral artery occlusion Mohamed AA;Gotoh O;Graham DI;Osbome KA;McCulloch J;Mendelow AD;Teasdale GM;Harper AM
  30. Kor J Anat. v.28 no.1 The distribution of substance P, neurotensin or vasoacive intrestinal polypeptide containing neu-rons and axon terminals in the periaqueductal gray of the rat Son El;Cho HJ;Hong HS;Kang J.
  31. J Comp Neurol. v.362 no.2 Vasopressin binding in the cerebral cortex of the Mongolian gerbil is reduced by transient cerebral iscemia Valley P;Bouras C;Barberis C;Dreifuss JJ;Dubios DM.
  32. Neuroscience v.38 Ischemia-induced slowly progressive neuronal damage in the rat brain Nakano S;Kogure K;Fujikura H.
  33. Acta Neuropathol. v.62 Fine structural nature of deleyed neuronal death following ischemia in the gerbil hippocampus Kirino T;Sano K.
  34. Acta Neuropathol. v.80 Ultrastructural investigation of the CA1 region of the hippocamupus after transient cerebral ischemia in gerbil Yamamoto K;Hayakawa T;Mogami H;Akai F;Yanagihara T
  35. Acta Neurpoathol. v.62 Selective vulnerability in the gerbil hippocampus following transient ischemia Kinno T;Sano K.
  36. Neurochem. v.19 Effect of metabolic ingibitors on the release of glutamate from the retina Van Harreveld A;Fifkova E
  37. Ann Neurol. v.11 Temporal profile of neuronal damage in a model of transient forebrain ischemia Pulsinelli WA;brierley JB;Plum F.
  38. Neurology v.37 Deleyed hippocampal demage in humans following cardiorespiratory arrest Pettro CK;Feldmann E;Pilsinelli WA;Plum F.
  39. Brain Res. v.483 Phenytoin protects against ischemia-produced neuronal cell death Traft WC;Clifton GL;Blair RE
  40. Progress in Neurobiology v.40 Mechanism and pathogenesis of ischemia-induced neuronal damage Hideaki H;Takayuki S;Kyuya K.