Biomedical Science Letters (대한의생명과학회지)
- Volume 6 Issue 1
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- Pages.45-53
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- 2000
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
Antioxidative Effects of Korean Red Ginseng Extracts on the Glutathione and Lipid Peroxidation in the Liver of Mouse Treated with Paraquat
홍삼추출물 투여 후 Paraquat가 투여된 생쥐간에서 Glutathione과 Lipid Peroxidation에 미치는 항산화 효과
Abstract
The anti-oxidative effects of Korean red ginseng extracts (total saponine, water extracts, alcohol extracts, lipophilic extracts), which were administered with the concentration of 200 mg/kg BW, were investigated after the injection of paraquat (1,1-dimethyl-4,4-bipyrimidinium dichloride: PQ) with dosage of 100 mg/kg BW on the peritoneal cavity to 6 weeks of 23~26 gm ICR male mice. The accumulation of hydrogen peroxide (
본 연구결과에서 볼 때 paraquat독성 생존율 실험에서는 ascorbic acid가 우수하였고, 간조직 내 과산화수소 (