YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Effect of the Aqueous Extract of Epimedium Koreanum Nakai on Melanin Formation in Bl6 Mouse Melanoma Cell Line

음양곽 물추출물이 Bl6 Mouse Melanoma 세포의 멜라닌 생성에 미치는 영향

  • 천현자 (원광대학교 한의학전문대학원) ;
  • 문연자 (원광대학교 한의학전문대학원) ;
  • 김정훈 (원광대학교 한의학전문대학원) ;
  • 김일광 (원광대학교 자연과학대학) ;
  • 전병훈 (원광대학교 한의과대학) ;
  • 우원홍 (원광대학교 한의학전문대학원)
  • Published : 2000.10.01
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Abstract

To investigate how the aqueous extracts of Epimedium koreanum Nakai (EK) affects pigmentation of skin, the aqueous extract of EK at various concentrations were incubated with 1 $\times$ 10$^{5}$ melanoma cells per well for 72 h. The morphology and number of cell line were not changed, but the aqueous extract of EK increased the tyrosinase activity and the content of melanin polymer in the cell line. These results indicate that the aqueous extract of EK promotes melanogenesis of Bl6 mouse melanoma cell line.

Keywords

References

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