YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

A PVC Liquid Membrane Electrodes for the Determination of Norfloxacin

PVC 액체막 전극을 이용한 Norfloxacin의 정량

  • 김동오 (경성대학교 약학대학) ;
  • 남수자 (경성대학교 약학대학) ;
  • 문현숙 (경성대학교 약학대학) ;
  • 정문모 (경성대학교 약학대학) ;
  • 허문회 (부산지방식품의약품안전청) ;
  • 김대병 (부산지방식품의약품안전청) ;
  • 안문규 (경성대학교 약학대학)
  • Published : 2000.10.01
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Abstract

The present method is to describe a potentiometric norfloxacin electrode system characterized by a membrane, based on the use of norfloxacin (NF) complex with ion-association reagents. These complexes were dissolved in DMSO, DMF acetonitrile or acetone and dispersed in plasticized poly(vinyl chloride) matrix. The picric acid complex electrode exhibited near-Nernstian response for NF in acetate buffer solution (pH 4.0) with a slope of 53.03 mV/decade. And linear response over the range of 10$^{-5}$ to 10$^{-3}$M solution of NE. The ingredients in tablet, capsule and biological important organic acids were not interfere.

Keywords

References

  1. The quinolones (2nd Ed.) Andriole
  2. Ind.J.Pharm.Sci. v.54 no.114 New colorimetirc method for the estimation of norfloxacin in formulations Mishra P.;Jain S.A.
  3. Fenxi Huaxue v.21 no.2 Charge transfer reaction and its application in the analytical chemistry Xuguang Z.;Jianzhang F;Shenyang T.
  4. Talanta v.42 no.311 Extractive spectrophotometric determination of some fluoroquinolone derivatives in pure and dosage forms Sastry C.S.P.;Rao K.R.;Prasad D.S.
  5. Anal.Chim.Acta v.300 no.253 Fluorescence reaction and complexation equilibria between norfloxacn and aluminium(III) ion in chloride medium Djurdjevic P.T.;Stankov M.J.;Stankov D.
  6. Analyst v.119 no.2351 Adsorptive differential-pulse stripping voltammetry ofnorfloxacin and its analytical application Jaber A.M.Y.;Lounici A.
  7. Yaowu Fenxi Zazhi v.15 no.33 The Study of adsorptive voltammetry for norfloxacin Xunjian L.;Guonan C.;Dongcun X.;ShoujianW.;Jianfang Z;Runqiang J.;Lizhu D.;Lan M.
  8. J.Chromatogr.A v.812 no.381 Determination of norfloxacin in human plasma and urine by high-performance liquid chromatography and fluorescence detection Mascher H.J.;Kikuta C.
  9. J.Chromatogr. v.812 no.343 Analysis of fluoroquinolones in biological fluids by high performance liquid chromatograpy Carlucci G.
  10. Anal.Chim.Acta v.268 no.307 A study of the prospects for a ciprofloxacin PVC coated wire ion-selective electrode based on 4-quinolones Avsec H.;Gomiscek S.
  11. Fenxi Huaxue v.24 no.3 Preparation and application of an ion-selective electrode norfloxaxcin Guo L.;Wang Y.Z.;Lim J.
  12. Fenxi Huaxue v.24 no.8 Preparation and application of a poly(vinyl chloride) membrane-selective electrode for norfloxacin Li D.H.;Wang M.;Ping Y.D.